iphepha_ibhena

imveliso

I-1-Boc-3-piperidone CAS 98977-36-7

Ipropati yeMichiza:

Ifomula yeemolekyuli C10H17NO3
IMisa yeMolar 199.25
Ukuxinana 1.099±0.06 g/cm3(Kuxelwe kwangaphambili)
Indawo yokunyibilika 35-40 °C (lit.)
Indawo yeBoling 289.8±33.0 °C(Kuxelwe kwangaphambili)
Indawo yokuflasha >230°F
Ukunyibilika kwamanzi Ayinyibiliki emanzini.
Uxinzelelo loMphunga 0.002mmHg kwi-25°C
Imbonakalo Okumhlophe okuqinileyo
Umbala Icacile engenambala
I-BRN 5936353
pKa -1.71±0.20(Kuxelwe kwangaphambili)
Imeko yoGcino 2-8°C
Refractive Index 1.481

Iinkcukacha zeMveliso

Iithegi zeMveliso

Umngcipheko kunye noKhuseleko

Inkcazelo yoKhuseleko 24/25-Kuphephe ukudibana nolusu kunye namehlo.
WGK eJamani 3
Ikhowudi ye-HS 29339900
IKlasi yeeNgozi GCINA KUBANDA

Ulwazi lweReference

Intshayelelo I-n-tert-butoxycarbonyl-3-piperidone sisibulali-zinambuzane esibalulekileyo, ikwayindawo ephakathi kwimiba yonyango kunye nezinye izongezo zekhemikhali. Kukho iindlela ezahlukeneyo ezikhoyo zokwenziwa: (1) usebenzisa i-γ-butyrolactone njengento ekrwada, emva kwe-benzylaminolysis, i-hydrolysis, i-esterification, i-condensation ne-ethyl bromoacetate, i-cyclization, i-reaction yamanyathelo amathandathu e-hydrolytic decarboxylation ivelisa i-1-benzyl-3-piperidone. i-hydrochloride, ilandelwa yi-debenzylation ye-tert-butoxycarbonyl iqela ukunika i-n-tert-butoxycarbonyl-3-piperidone (US0053565). (2) kunye ne-3-hydroxypyridine njengento eluhlaza, ukuphendula nge-benzyl bromide ukuvelisa ityuwa ye-quaternary ammonium, ukunciphisa i-sodium borohydride, i-Palladium carbon debenzyl kwi-tert-butoxycarbonyl, i-N-tert-butoxycarbonyl-3-piperidone (CN103204801) yafunyanwa yi-low- ubushushu be-oxidation ye-dimethyl sulfoxide.
Isicelo I-n-tert-butoxycarbonyl-3-piperidone yinto ephakathi kwi-organic synthesis kunye ne-intermediate kumayeza, ingasetyenziselwa uphando lwebhubhoratri kunye nenkqubo yophuhliso kunye nenkqubo ye-chemical medicine synthesis process, esetyenziselwa ikakhulu kwi-stereo control synthesis ye-chiral compounds.
Sebenzisa I-N-tert-butoxycarbonyl-3-piperidone isetyenziselwa i-stereologically controlled synthesis ye-chiral compounds.

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