1H-Pyrazole-3-carboxylicacid 5-methyl-(CAS# 696-22-0)
| Iimpawu ezinobungozi | Xi – Irritant |
| Iikhowudi zoMngcipheko | R36/37/38 – Ukucaphuka kwamehlo, inkqubo yokuphefumla kunye nolusu. |
| Inkcazelo yoKhuseleko | S26 – Xa udibana namehlo, hlambulula ngokukhawuleza ngamanzi amaninzi kwaye ufune iingcebiso zonyango. I-S37/39 -Nxiba iiglavu ezifanelekileyo kunye nokukhusela amehlo / ubuso |
Intshayelelo
I-organic compound kunye ne-chemical formula C5H5N2O2. Iqhelekile ukuba yikristale engenambala ukuya koluthubi.
Ikhompawundi inamaqela amabini asebenzayo, enye yindandatho yepyrazole kwaye enye liqela elisebenzayo le-carboxylic acid. Inonyibiliko oluphakathi kwaye iyanyibilika emanzini nakwizinyibilikisi eziqhelekileyo zendalo. Iqela le-methyl kwisakhiwo sayo lenza i-hydrophobic.
Njengomxube we-heterocyclic, i-5-methyl-inemisebenzi eyahlukeneyo yezinto eziphilayo. Isetyenziswa kakhulu kuphando lwamachiza kunye nokuhlanganiswa kweziyobisi, kaninzi njengento ekrwada okanye ephakathi. Ukusetyenziswa okuthe ngqo kubandakanya ukuhlanganiswa kwe-vitamin B1 analogues, i-insecticide, i-plavix inhibitors (ikhompawundi esetyenziselwa ukuthintela ukukhula kwezityalo), kunye nokunye okunjalo.
Ukulungiselela, i-5-methyl-inokufumaneka ngokuphendula i-athomu ye-nitrogen ye-pyrazole ring kunye ne-methylating agent (umz. i-methyl iodide). Le ndlela iqhutyelwa yi-N-methylation reaction, indlela eqhelekileyo yokusabela kwe-nucleophile ehambelanayo ne-N-methyl reagent.
