Ifowuni: +86 21 6460 6569
iphepha_ibhena

imveliso

2-Amino-6-bromopyridine (CAS# 19798-81-3) Umfanekiso obonakalayo
  • 2-Amino-6-bromopyridine (CAS# 19798-81-3) 1

2-Amino-6-bromopyridine (CAS# 19798-81-3)

Ipropati yeMichiza:

Ifomula yeemolekyuli I-C5H5BrN2
IMisa yeMolar 173.01
Ukuxinana 1.710±0.06 g/cm3(Kuxelwe kwangaphambili)
Indawo yokunyibilika 88-91 °C (lit.)
Indawo yeBoling 273.0±20.0 °C(Kuxelwe kwangaphambili)
Indawo yokuflasha 118.9°C
Ukunyibilika kwamanzi Inyibilika kancinane emanzini.
Ukunyibilika I-Chloroform (Kancinci), iMethanol (Kancinci kakhulu)
Uxinzelelo loMphunga 0.0059mmHg ku-25°C
Imbonakalo Umgubo omhlophe ukuya kumdaka omdaka
Umbala Mthubi kancinci ukuya kumdaka okhanyayo
pKa 2.73±0.24(Kuxelwe kwangaphambili)
Imeko yoGcino Gcina kwindawo emnyama, itywinwe kwindawo eyomileyo, ubushushu beGumbi

Iinkcukacha zeMveliso

Iithegi zeMveliso

Umngcipheko kunye noKhuseleko

Iikhowudi zoMngcipheko R36/37/38 – Ukucaphuka kwamehlo, inkqubo yokuphefumla kunye nolusu.
I-R20/21/22 – Iyingozi ngokuphefumla, xa udibana nolusu naxa uginyiwe.
Inkcazelo yoKhuseleko S26 – Xa udibana namehlo, hlambulula ngokukhawuleza ngamanzi amaninzi kwaye ufune iingcebiso zonyango.
S36 – Nxiba iimpahla ezifanelekileyo ezikhuselayo.
S36/37/39 – Nxiba iimpahla ezifanelekileyo zokukhusela, iiglavu kunye nokukhusela amehlo/ubuso.
WGK eJamani 3
Ikhowudi ye-HS 29333999
IKlasi yeeNgozi OKUTHUMEKAYO

 

 

2-Amino-6-bromopyridine (CAS# 19798-81-3) Ulwazi

Isishwankathelo I-2-amino efakwe endaweni ye-nitrogen ene-heterocyclic enamalungu amathandathu anezicelo ezibalulekileyo kwishishini lemichiza, njenge-2-amino -6-Bromopyridine yenye yezakhiwo ezibalulekileyo kumachiza okwenziwa kunye neemolekyuli zemichiza yezolimo, kwaye isetyenziswa ngokubanzi kwi-synthesis. yeemveliso zendalo, iziyobisi, izinto zokukhanyisa kunye neekhemikhali ezahlukeneyo ezintle.
Isicelo I-2-amino efakwe endaweni ye-nitrogen ene-6-membed heterocyclic compounds inezicelo ezibalulekileyo kwishishini lemichiza, njenge-2-amino -6-Bromopyridine yenye yezakhiwo ezibalulekileyo kumachiza okwenziwa kunye neemolekyuli zemichiza yezolimo, kwaye isetyenziswa ngokubanzi kwi-synthesis. yeemveliso zendalo, iziyobisi, izinto zokukhanyisa kunye neekhemikhali ezahlukeneyo ezintle.
Ukulungiselela Ukulungiswa kwe-2-amino-6-bromopyridine: Yongeza i-2-fluoro-6-bromo-pyridine (1mmol), i-pentamidine hydrochloride (2mmol), i-sodium tert-butoxide (3mmol), i-HO (0.5mL) kunye ne-diethylene glycol dimethyl ether (2.5) mL) kwi-25 ml yokusabela ityhubhu. Ukusabela kwenziwa kwi-150 ℃ kwiiyure ezingama-24. Emva kokuba impendulo igqityiwe, yapholiswa kwiqondo lokushisa. Yongeza i-10mL ye-ethyl acetate ukucima impendulo, yongeza i-6mL yamanzi etyuwa ehluthiweyo ukuhlamba, ukwahlula isigaba se-organic, uze ukhuphe isigaba se-aqueous nge-ethyl acetate ngamaxesha e-3 (i-dosage ye-ethyl acetate ixesha ngalinye yi-6mL) kwaye udibanise i-organic isigaba, yongeza i-anhydrous sodium sulfate ukuze yome, susa i-solvent kuquka i-solvent ye-organic kunye ne-solvent ye-inorganic nge-vacuum i-distillation, kwaye emva koko uhlukanise i-solvent ye-organic ngekholomu ye-chromatography ukufumana imveliso ekujoliswe kuyo 2-amino-6-bromopyridine kunye nesivuno se-93%.
sebenzisa abaphakathi bamayeza.
ukuhlanganiswa okusebenzayo kwe-7-azafindole embizeni enye; ukwenzela ukuhlanganiswa kwamachiza alwa ne-HIV

 

  • Ngaphambili:
  • Okulandelayo:
    • Bhala umyalezo wakho apha kwaye uwuthumele kuthi

    iimveliso ezinxulumene