3 6-Dihydro-2H-pyran-4-boronic acid pinacol ester (CAS # 287944-16-5)
| Iimpawu ezinobungozi | Xn – Iyingozi |
| Iikhowudi zoMngcipheko | 22 – Iyingozi xa iginyiwe |
| Inkcazelo yoKhuseleko | S20 – Xa usebenzisa, ungatyi okanye usele. S35 – Esi sixhobo kunye nesingxobo saso kufuneka silahlwe ngendlela ekhuselekileyo. |
| WGK eJamani | 3 |
| Ikhowudi ye-HS | 29349990 |
Intshayelelo
3. i-acid pinacol ester yi-organic compound kunye ne-chemical formula ye-C12H19BO3 kunye nobunzima be-molecular 214.09g / mol.
Indalo:
-Imbonakalo: Ulwelo olungenambala okanye oluqinileyo
-Indawo yokunyibilika:-43 ~-41 ℃
-Indawo yokubilisa: 135-137 ℃
-Ubuninzi: 1.05 g/mL
-I-Solubility: I-Soluble kwii-solvents eziqhelekileyo ezifana ne-dimethylformamide, i-dichloromethane, i-methanol kunye ne-ethanol.
Sebenzisa:
- 3, acid pinacol ester yenye intermediates ebalulekileyo synthesis eziphilayo. Ingasetyenziswa njenge-reagent yokwakhiwa kweebhondi ze-C-O kunye ne-C-C, kwaye isoloko isetyenziswa njenge-catalyst ye-C-C yokudibanisa iimpendulo ezifana ne-Suzuki reaction kunye ne-Stille reaction.
-I-compound ingasetyenziselwa ukulungiselela amanye amaqela asebenzayo okanye ama-compounds, afana ne-aldehydes, i-ketones kunye ne-acids.
Indlela:
- 3, i-acid pinacol ester ilungiswa ngokubanzi ngokusabela kwiPyran kunye ne-boronic acid pinacol phantsi kwe-alkali catalysis. Indlela ethile yokulungiselela ingakhethwa ngokweemfuno zokwenyani, kwaye indlela yokulungiselela eqhelekileyo ibandakanya ukusebenzisa iborate yesodium kunye nepinacol ukusabela phantsi kweemeko zealkaline.
Ulwazi ngoKhuseleko:
3, acid pinacol ester kunokuba yingozi empilweni kunye nokusingqongileyo. Ukusetyenziswa kufanele kulandele iinkqubo ezifanelekileyo zaselabhoratri kwaye kuxhotyiswe ngezixhobo eziyimfuneko zokuzikhusela, ezinjengeeglavu zaselabhoratri kunye nokhuseleko lwamehlo.
Ukongeza, ulwazi oluthile lokhuseleko kunye nemiyalelo yokusebenza kufuneka ibhekiselele kwiphepha ledatha yokhuseleko lwekhompawundi (SDS) okanye enye ireferensi yeekhemikhali ethembekileyo.
