3-Chloro-5-(trifluoromethyl)pyridine(CAS# 85148-26-1)
| Iikhowudi zoMngcipheko | I-R20/21/22 – Iyingozi ngokuphefumla, xa udibana nolusu naxa uginyiwe. R36/37/38 – Ukucaphuka kwamehlo, inkqubo yokuphefumla kunye nolusu. I-R25 – Inetyhefu xa iginyiwe |
| Inkcazelo yoKhuseleko | S26 – Xa udibana namehlo, hlambulula ngokukhawuleza ngamanzi amaninzi kwaye ufune iingcebiso zonyango. S36/37/39 – Nxiba iimpahla ezifanelekileyo zokukhusela, iiglavu kunye nokukhusela amehlo/ubuso. S36 – Nxiba iimpahla ezifanelekileyo ezikhuselayo. S45 - Kwimeko yengozi okanye ukuba uziva ungaphilanga, funa iingcebiso zonyango ngokukhawuleza (bonisa ileyibhile nanini na kunokwenzeka.) |
| Izazisi ze-UN | UN 2811 6.1 / PGIII |
| WGK eJamani | 3 |
| Inqaku Lengozi | Iyacaphukisa |
| IKlasi yeeNgozi | IRRITANT, IRRITANT-H |
| Iqela lokuPakisha | III |
Intshayelelo
I-3-choro-5-(trifluoromethyl) pyridine yi-organic compound ene-chemical formula C≡H₂ ClFΛ N. Lulwelo olungenambala ukuya kumthubi oluluthulu olunevumba elinukayo. Oku kulandelayo yinkcazo yendalo, ukusetyenziswa, ukulungiswa kunye nolwazi lokhuseleko lwe-3-choro-5-(trifluoromethyl)pyridine:
Indalo:
-Ubuninzi: 1.578 g/mL
-Indawo yokubila: 79-82 ℃
-Indawo yokunyibilika:-52.5 ℃
-Ukunyibilika: Inyibilika kwizinyibilikisi eziphilayo ezifana ne-ethanol, i-ether kunye ne-dichloromethane, i-soluble kancinane emanzini.
Sebenzisa:
-Njengama-reagents kunye ne-intermediates kwi-organic synthesis, esetyenziswa kwi-synthesis ye-pesticides, iziyobisi kunye nezinye izinto eziphilayo.
-Kuphando kwintsimi yeyeza, ezifana ne-synthesis ye-anti-cancer drug and biomarkers.
Indlela yokulungiselela:
I-3-chloro-5-(trifluoromethyl)pyridine inokulungiswa ngezi ndlela zimbini zilandelayo:
1. Ukusebenzisa i-pyridine njengento eluhlaza, i-chlorination reaction yenziwa phambi kwe-hydrochloric acid, kwaye emva koko i-trifluoromethylation reaction yenziwa phambi kwe-sodium trifluoromethylate.
2. Ukusebenzisa i-3-picolinic acid njengento eluhlaza, i-chlorination reaction yenziwa phambi kwe-thionyl chloride, kwaye ke i-trifluoromethylation reaction yenziwa phambi kwe-trifluoromethyl mercaptan.
Ulwazi ngoKhuseleko:
- 3-chloro-5-(trifluoromethyl)pyridine iyacaphukisa kwaye inokubangela ukucaphuka xa udibana nolusu kunye namehlo. Kuyimfuneko ukunxiba imilinganiselo yokukhusela efanelekileyo xa usebenzisa, njengokunxiba iindondo zokukhusela, iiglavu kunye nempahla ekhuselayo.
-Kuphephe ukuphefumla umphunga kwaye uqinisekise ukuba umsebenzi wenziwa kwindawo engenamoya.
-Xa ugcina, yigcine kwisitya esivaliweyo, kude nomlilo kunye ne-oxidizing agents.
-Xa ulahla inkunkuma, yiphathe kwaye uyilahle ngokuhambelana nemimiselo yendawo.
-Nceda ujonge iPhepha leDatha loKhuseleko elifanelekileyo (SDS) ngolwazi oluthe vetshe ngokhuseleko.
