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3-methyl-2-oxobutyric acid (CAS# 759-05-7) Umfanekiso okhoyo
  • 3-methyl-2-oxobutyric acid (CAS# 759-05-7) 1

I-3-methyl-2-oxobutyric acid (i-CAS # 759-05-7)

Ipropati yeMichiza:

Ifomula yeemolekyuli C5H8O3
IMisa yeMolar 116.12
Ukuxinana 0.9968
Indawo yokunyibilika 31.5℃
Indawo yeBoling 170.5℃
Inombolo yeJECFA 631
Ukunyibilika kwamanzi 400.6g/L(20 ºC)
pKa 2.57±0.54(Kuxelwe kwangaphambili)
Imeko yoGcino 2-8°C
Refractive Index 1.3850
Isifundo se-in vitro I-3-Methyl-2-oxobutanoic acid (i-alpha-Ketoisovaleric acid) isandulela se-pantothenic acid kwi-Escherichia coli. I-3-Methyl-2-oxobutanoic acid (i-alpha-Ketoisovaleric acid) iphucula i-alpha-ketoisocaproic acid kunye ne-alpha-keto-beta-methyl-n-valeric acid, kodwa iyancipha i-amino acids ehambelanayo, kwaye ibangela ukwehla kwangaphambili kwe-ornithine kunye ukwanda kade kwe-plasma arginine.
Kwisifundo se-vivo I-3-Methyl-2-oxobutanoic acid (i-alpha-Ketoisovaleric acid) ibangela ukuxhatshazwa ngeendlela ze-GABAergic kunye ne-glutamatergic kwiigundane.

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Intshayelelo

I-3-Methyl-2-oxobutyric acid, eyaziwa ngokuba yi-tert-butoxypropionic acid, i-TBAOH, i-organic compound.

 

Umgangatho:

I-3-Methyl-2-oxobutyric acid lulwelo olungenambala ukuya kumthubi oluluthuthu olunevumba elingaqhelekanga. Inokunyibilika emanzini nakwizinyibilikisi ezininzi zezinto eziphilayo, kodwa ayinyibiliki kwizinyibilikisi ezingezizo ipolar ezifana ne-petroleum ethers.

 

Sebenzisa:

I-3-Methyl-2-oxobutyric acid idla ngokusetyenziswa njenge-alkali catalyst kwi-organic synthesis, ngakumbi kwiimpendulo zokutshintshwa. Iyakwazi ukuvuselela iintshukumo ezifana ne-esterification, i-etherification, i-amidation, i-olefin Ukongeza, njl.

 

Indlela:

I-3-Methyl-2-oxobutyric acid inokufumaneka ngokuphendula ipropanol kunye ne-sodium tert-butoxide (okanye i-tert-butanol kunye ne-sodium hydroxide). Isinyathelo esithile kukusabela kwipropanol nge-tert-butyl sodium oxide kwiqondo lokushisa elifanelekileyo, kwaye ke imveliso ifunyenwe ngokucima.

 

Ulwazi ngoKhuseleko:

I-3-Methyl-2-oxobutyric acid iyacaphukisa kwaye iyatshisa kwaye kufuneka igwenywe ekudibaneni nolusu, amehlo, kunye nokuphefumula. Iiglavu ezikhuselayo, iiglasi, kunye nemaski kufuneka zinxitywe ngexesha lokusetyenziswa. Kwimeko yokudibana ngengozi, hlambulula ngamanzi amaninzi kwaye ufune unyango ngokukhawuleza. Kufuneka igcinwe kwindawo epholileyo, engenamoya, kude nomlilo kunye ne-oxidants.

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