5-amino-2-fluorobenzoic acid (CAS# 56741-33-4)
| Iikhowudi zoMngcipheko | R36/37/38 – Ukucaphuka kwamehlo, inkqubo yokuphefumla kunye nolusu. I-R22 – Iyingozi xa iginyiwe |
| Inkcazelo yoKhuseleko | S26 – Xa udibana namehlo, hlambulula ngokukhawuleza ngamanzi amaninzi kwaye ufune iingcebiso zonyango. S36 – Nxiba iimpahla ezifanelekileyo ezikhuselayo. S37 – Nxiba iiglavu ezifanelekileyo. |
| Ikhowudi ye-HS | 29163990 |
| Inqaku Lengozi | Iyacaphukisa |
Intshayelelo
I-5-amino-2-fluorobenzoic acid yi-organic compound kunye ne-chemical formula C7H6FNO2. Yikristale emhlophe eqinileyo, izinzile kubushushu begumbi. Oku kulandelayo yinkcazo yobume bayo, ukusetyenziswa, ukulungiswa kunye nolwazi lokhuseleko:
Indalo:
1. Ukubonakala: I-5-amino-2-fluorobenzoic acid i-white crystalline solid.
2. Ukunyibilika: Ine-solubility ephantsi emanzini kwaye inokunyibilika kancinane kwizinyibilikisi ze-organic ezifana ne-ethanol kunye ne-ketone.
3. Ukuzinza kwe-Thermal: Inozinzo oluhle lwe-thermal kwaye akulula ukubola ngexesha lokufudumala.
Sebenzisa:
I-5-amino-2-fluorobenzoic acid yinto ebalulekileyo ephakathi kwi-organic synthesis kwaye isetyenziswa ngokuqhelekileyo kumashishini amayeza kunye nedayi.
1. Ukusetyenziswa kwamachiza: Ingasetyenziselwa ukudibanisa amanye amachiza, njenge-clozapine.
2. Ukusetyenziswa kwedayi: Ingasetyenziswa njengesandulela sedayi yokwenziwa kwedayi ethile enemibala.
Indlela yokulungiselela:
Iindlela zokulungiselela i-5-amino-2-fluorobenzoic acid ikakhulu ziquka ezi zilandelayo:
1. Ukuphendula kwe-Fluorination: I-2-fluorobenzoic acid kunye ne-ammonia iphendulwa kunye ne-catalyst yokufumana i-5-amino-2-fluorobenzoic acid.
2. Diazo reaction: lungisa kuqala i-diazo compound ye-2-fluorobenzoic acid, kwaye emva koko uphendule nge-ammonia ukuvelisa i-5-amino-2-fluorobenzoic acid.
Ulwazi ngoKhuseleko:
Ulwazi lokhuseleko kwi-5-amino-2-fluorobenzoic acid ifuna uphando olongezelelweyo kunye nokuqinisekiswa kovavanyo. Ukusetyenziswa kufuneka kuthathelwe ingqalelo kula manqaku alandelayo:
1. Gwema ukudibanisa: thintela ukudibanisa nolusu, amehlo kunye nomgudu wokuphefumula. Hlanza ngamanzi acocekileyo ngoko nangoko emva kokudibana.
2. Qaphela ukugcina: Gcina kwindawo eyomileyo, epholileyo, kude nomlilo kunye nezinto ezinokutsha.
3. Inqaku lokusebenza: ekusebenziseni inkqubo kufuneka inxibe iiglavu ezikhuselayo, iiglasi kunye neemaski, ukuqinisekisa ukungena komoya kakuhle.
