I-6-bromopyridine-2-carboxylic acid ethyl ester (CAS # 21190-88-5)
| Iimpawu ezinobungozi | Xi – Irritant |
| Iikhowudi zoMngcipheko | 36 – Ukucaphukisa emehlweni |
| Inkcazelo yoKhuseleko | I-26 - Kwimeko yokunxibelelana namehlo, hlambulula ngokukhawuleza ngamanzi amaninzi kwaye ufune iingcebiso zonyango. |
Intshayelelo
i-acid ethyl ester yi-organic compound kunye ne-chemical formula C8H8BrNO2. Ilulwelo olungenambala olunevumba elikhethekileyo. Ikhompawundi iyanyibilika kwii-solvents eziphilayo ezifana ne-ethanol, i-dimethylformamide kunye ne-benzene, kwaye ayinyibiliki emanzini.
i-acid ethyl ester inoluhlu olubanzi lwezicelo kwi-organic synthesis. Ingasetyenziselwa njenge-pharmaceutical intermediate ye-synthesis yoluhlu olubanzi lwamachiza kunye ne-bioactive molecules. Ukongeza, inokusetyenziswa kwi-reaction ye-Gormperman kunye ne-palladium-catalyzed cross-coupling reactions kwi-organic synthesis.
Kukho iindlela ezimbini eziqhelekileyo ze-acid ethyl ester:
1. Ifunyenwe ngokuphendula kwe-6-bromopyridine kunye ne-chloroacetate, kwaye i-hydrolyzed nge-alkali emva kokuphendula.
2. Nge-6-bromopyridine kunye ne-chloroacetic acid ester reaction, i-acid chloride, uze uphendule ngotywala ukuze ufumane imveliso.
Izilumkiso zokhuseleko ziyafuneka xa usebenzisa kwaye ugcina i-acid ethyl ester. Lulwelo olunokutsha kwaye kufuneka lugcinwe kwindawo epholileyo nengena umoya, kude nomlilo namaqondo obushushu aphezulu. Izixhobo ezifanelekileyo zokukhusela, ezinjengeeglavu zelebhu kunye neglavu, kufuneka zinxitywe ngexesha lokusebenza. Ukuba ukungeniswa okanye ukudibana nesikhumba okanye amehlo, hlambulula ngokukhawuleza ngamanzi amaninzi kwaye ufune uncedo lwezonyango.
