BOC-D-2-Amino butyric acid (CAS# 45121-22-0)
| IKlasi yeeNgozi | OKUTHUMEKAYO |
Intshayelelo
I-Boc-D-Abu-OH(Boc-D-Abu-OH) yikhompawundi ephilayo eneempawu ezilandelayo:
1. imbonakalo kunye neempawu: imeko eqhelekileyo yomzimba yikristale emhlophe okanye i-crystalline powder.
Iimpawu ze-2 zekhemikhali: luhlobo lwe-amide compounds, lune-solubility efanelekileyo, kwi-solvents ye-organic (njenge-dimethyl sulfoxide, i-dichloromethane, i-acetone, njl.) kwi-solubility ephezulu.
3. Uzinzo: uzinzile phantsi kweemeko eziqhelekileyo, kodwa ukudibanisa nee-oxidants ezinamandla kunye neemeko eziphezulu zokushisa kufuneka kugwenywe.
Izicelo ze-Boc-D-Abu-OH zigxininiswe kakhulu kwintsimi ye-organic synthesis, edla ngokusetyenziswa kwi-chemistry yamachiza kunye nophando lwe-biochemistry, izicelo ezithile ziquka:
1. I-peptide synthesis: njengeqela elikhuselayo, linokuba kwinkqubo ye-peptide synthesis yokukhusela iqela le-amine, ukulikhusela ekuphenduleni okungaqhelekanga.
2. i-chiza synthesis: inokusetyenziswa njengendawo ephakathi ukulungiselela iimolekyuli zamachiza ezinokubakho kunye neekhompawundi zabaviwa beziyobisi.
3. Izifundo zezinto eziphilayo: I-Boc-D-Abu-OH i-derivatives ingasetyenziselwa ukuvavanya umsebenzi webhayoloji kunye neempawu ze-pharmacokinetic ze-compounds ezithile.
Indlela yokulungiselela i-Boc-D-Abu-OH idla ngokufezekiswa ngala manyathelo alandelayo:
1. Sebenzisa ii-reagents ezifanelekileyo ukuguqula i-methyl propionate kwi-dimethyl sulfoxide kwi-N-BOC-alanine methyl ester.
2. I-N-BOC-alanine methyl ester iphinda ihlaziywe phantsi kweemeko ze-alkaline ukuvelisa i-Boc-D-Abu-OH.
malunga nolwazi lokhuseleko lwe-Boc-D-Abu-OH, la manqaku alandelayo kufuneka aqatshelwe:
1. Ukuqwalasela ukuba yikhemikhali, kufuneka iphathwe kwaye igcinwe ngokuchanekileyo, kuphephe ukudibana nolusu kunye namehlo, kwaye igcinwe kude nomlilo.
2. esetyenziswayo kufuneka ilandele iinkqubo zokhuseleko lwebhubhoratri.
3. Ukwenzela uvavanyo lokhuseleko lweekhemikhali, makudityanwe namaxwebhu edatha okhuseleko afanelekileyo kunye noncwadi ukuqinisekisa ukusetyenziswa ngokuchanekileyo nangokukhuselekileyo.
