I-Boc-D-aspartic acid 4-benzyl ester (CAS# 51186-58-4)

Intshayelelo

i-tert-Butoxycarbonyl-D-aspartic acid i-4-benzyl ester (i-Boc-D-aspartic acid 4-benzyl ester) i-organic compound. Oku kulandelayo yinkcazo yeepropati, ukusetyenziswa, ukulungiswa kunye nolwazi lokhuseleko lwekhompawundi:

Indalo:

-Imbonakalo: Ikristale emhlophe eqinileyo

-Ifomula yemolekyuli: C16H21NO6

-Ubunzima bemolekyuli: 323.34g / mol

-indawo yokunyibilika: 104-106 ℃

-Ukunyibilika: Inyibilika kwizinyibilikisi eziqhelekileyo eziphilayo (ezifana ne-ether, i-methanol, i-ethanol)

Sebenzisa:

-tert-Butoxycarbonyl-D-aspartic acid 4-benzyl ester isetyenziswa kakhulu njenge-reagent kuphando lwe-biochemical, esetyenziselwa ukudibanisa okanye ukuguqula ezinye izinto eziphilayo.

-Ihlala isetyenziswa kwi-peptide synthesis njengeqela elikhuselayo le-aspartic acid ukukhusela iqela elisebenzayo kwicala le-amino acid chain kwaye lenze impendulo yokukhusela xa kufuneka.

Indlela yokulungiselela:

-Ngokubanzi, i-Boc-D-aspartic acid i-4-benzyl ester ilungiswa ngokusabela kwe-aspartic acid. Okokuqala, i-aspartic acid iphendulwa nge-acetyl chloride (AcCl) ukunika i-aspartic acid acetyl ester. I-acetyl ekhuselweyo i-aspartate i-acetyl ester iphinda isetyenziswe nge-tert-butoxycarbonyl chloride (Boc-Cl) ukunika i-tert-butoxycarbonyl-D-aspartate 4-acetyl ester. Ekugqibeleni, i-tert-butoxycarbonyl-D-aspartic acid 4-benzyl ester inokufumaneka nge-esterification ye-benzyl alcohol kunye nesiseko.

Ulwazi ngoKhuseleko:

- I-Boc-D-aspartic acid 4-benzyl ester ngokubanzi inetyhefu ephantsi, kuseyimfuneko ukuthatha amanyathelo afanelekileyo okukhusela ngexesha lokusebenza, njengokugqoka iiglavu, izibuko kunye neengubo zebhubhoratri.

-Kuphephe ukudibana nolusu kunye nokuphefumla uthuli.

-Yigcine kwindawo eyomileyo, epholileyo, kude nomlilo kunye ne-oxidizing agents.

-Xa uphatha kwaye ulahla, nceda ulandele iinkqubo ezifanelekileyo zokusebenza kunye nemimiselo yokhuseleko.