I-Boc-D-Glutamic acid 5-benzyl ester (CAS# 35793-73-8)
| Inkcazelo yoKhuseleko | S22 – Musa ukuphefumla uthuli. S24/25-Kuphephe ukudibana nolusu namehlo. |
| WGK eJamani | 3 |
Intshayelelo
I-Boc-D-Glu (OBzl)-OH (Boc-D-Glu (OBzl)-OH) i-organic compound. Oku kulandelayo yinkcazo yobume bayo, ukusetyenziswa, ukuqulunqwa kunye nolwazi lokhuseleko:
Indalo:
-Imbonakalo: Umgubo omhlophe wekristale
-Ifomula yemolekyuli: C20H25NO6
-Ubunzima beMolekyuli: 379.41
-Indawo yokunyibilika: 118-120 ℃
-Ukunyibilika: Inyibilika kwezinye izinyibilikisi eziphilayo, ezifana ne-methanol kunye ne-dichloromethane
Sebenzisa:
- I-Boc-D-Glu (OBzl) -OH isetyenziswa ngokuqhelekileyo kwintsimi ye-drug synthesis kunye ne-peptide synthesis.
-Ingasetyenziselwa njengeqela elikhuselayo leepeptide ukukhusela iqela elisebenzayo le-hydroxyl ye-glutamic acid ngexesha lenkqubo yokudibanisa ukukhusela iimpendulo ezingathandekiyo ngexesha lokuphendula.
Indlela yokulungiselela:
- I-Boc-D-Glu (OBzl) -OH idla ngokulungiswa nge-chemical synthesis.
-Okokuqala, i-tert-butoxycarbonyl (i-Boc) ifakwe kwi-molecule ye-glutamic acid ukuvelisa i-tert-butoxycarbonyl-D-glutamic acid (Boc-D-Glu).
-Emva koko, iqela le-benzyl (Bzl) lingeniswa kwiqela le-hydroxyl ye-glutamic acid ukwenza i-Boc-D-Glu (OBzl) -OH (Boc-D-Glu (OBzl) -OH).
Ulwazi ngoKhuseleko:
- I-Boc-D-Glu (OBzl) -OH i-organic compound, enokubangela ukucaphuka okuthile kunye nokulimala kumzimba womntu.
-Ngexesha lokusetyenziswa, qaphela ukuba ugweme ukudibanisa nesikhumba, amehlo kunye nokuphefumula.
-Kwimisebenzi yaselabhoratri okanye kwimveliso yemizi-mveliso, izixhobo ezifanelekileyo zokuzikhusela kufuneka zisetyenziswe, njengeiglavu, iiglasi ezikhuselayo kunye neemaski ezikhuselayo.
-Gcina kude nomlilo kunye ne-oxidizing agents, gcina i-container ivaliwe, kwaye uyigcine kwindawo epholileyo neyomileyo.
Nceda uqaphele ukuba olu lulwazi ngokubanzi kuphela kwaye aluhambelani neemeko ezithile zovavanyo kunye neendlela ezikhuselekileyo. Ngaphambi kokusebenzisa le khompawundi, kuyacetyiswa ukuba udibane nephepha ledatha elineenkcukacha zokhuseleko lwekhemikhali (MSDS) kwaye ulandele iindlela ezifanelekileyo zokhuseleko.
