I-Boc-L-aspartic acid 1-benzyl ester (CAS# 30925-18-9)
| Inkcazelo yoKhuseleko | 24/25-Kuphephe ukudibana nolusu kunye namehlo. |
| WGK eJamani | 3 |
| Ikhowudi ye-HS | 29242990 |
Intshayelelo
I-Boc-Asp-OBzl(Boc-Asp-OBzl) yikhompawundi eneempawu ezilandelayo:
1. Imbonakalo: Ikristale emhlophe eqinileyo.
2. Ifomula yemolekyuli: C24H27N3O7.
3. Ubunzima bemolekyuli: 469.49g/mol.
4. Indawo yokunyibilika: malunga ne-130-134 ° C.
I-Boc-Asp-OBzl isetyenziswa ngokubanzi kwi-biochemistry kunye ne-synthetic organic chemistry, ehlala isetyenziswa kwi-synthesis ye-peptides, iiprotheni kunye neziyobisi, ngokusetyenziswa okulandelayo:
1. I-Peptide synthesis: Njengenxalenye yeqela elikhuselayo (iqela le-Boc elikhuselayo), iqela le-amino kwi-aspartic acid amino acid inokukhuselwa.
2. Uphando lweziyobisi: ukuhlanganiswa kweziyobisi ze-peptide kunye ne-anti-inflammatory, anti-tumor kunye nomsebenzi wokulawula i-immune.
3. Ukusabela kwe-Enzyme: I-Boc-Asp-OBzl ingasetyenziselwa i-enzyme catalyzed reaction substrate.
Indlela yokulungiselela i-Boc-Asp-OBzl yile ilandelayo:
I-Aspartic acid kunye ne-benzoyl chloride zi-esterified ukwenza i-tert-butoxycarbonyl-aspartic acid benzyl ester (i-Boc-Asp-OMe), ethi emva koko iphendule nge-sodium hexoxide ukufumana i-intermediate ngendlela ye-N-hexanoate. Ekugqibeleni, ifumana impendulo ye-benzoylation ukuvelisa i-Boc-Asp-OBzl.
Nika ingqalelo kolu lwazi lulandelayo lokhuseleko xa usebenzisa i-Boc-Asp-OBzl:
1. Ikhompawundi inokubangela ukucaphuka kunye nokuchasana nomzimba womntu, kwaye ukudibana ngqo nolusu kunye namehlo kufuneka kuphetshwe.
2. Amanyathelo afanelekileyo okuzikhusela kufuneka athathwe ngexesha lokusebenza, njengokunxiba iiglavu kunye nezibuko.
3. Gcina womile kwaye uvalwe ngexesha lokugcina, kwaye ugcine kude nomlilo kunye ne-oxidant.
4. Xa usebenzisa kunye nokuphatha i-Boc-Asp-OBzl, nceda ulandele iinkqubo ezichanekileyo zokusebenza kwebhubhoratri kunye nokusebenza ngokukhuselekileyo.
Nceda uqaphele ukuba xa usebenzisa i-Boc-Asp-OBzl okanye nayiphi na imichiza, kufuneka ulandele ngokungqongqo izikhokelo zokusebenza ezihambelanayo zokhuseleko, kwaye wenze ukhuseleko lomntu kunye novavanyo lomngcipheko ngokweyona meko.
