I-Boc-L-Glutamic acid 1-benzyl ester (CAS# 30924-93-7)

Intshayelelo

I-Boc-L-Glutamic acid i-1-benzyl ester (i-Boc-L-Glutamic acid 1-benzyl ester) i-organic compound ene-chemical formula ye-C17H19NO6 kunye ne-molecular mass ye-337.34. Iqinile emhlophe, i-soluble kwii-solvents eziphilayo ezifana ne-ethanol, i-dimethylformamide kunye ne-chloroform.

I-Boc-L-Glutamic acid 1-benzyl ester isetyenziswa ngokuqhelekileyo kwi-synthesis ye-peptide compounds. Ingasetyenziselwa njenge-agent ye-micellar okanye iqela elikhuselayo lokukhusela iqela le-amino acid ukukhusela ukuphendulwa kwecala elingafunekiyo kwi-chemical reaction, kwaye ngexesha elifanayo linokuphucula isivuno. Ukongeza, inokusetyenziselwa ukuhlanganiswa kwamachiza e-polypeptide kunye neemolekyuli ezinxulumene ne-bioactive.

Indlela yokulungiselela i-Boc-L-Glutamic acid 1-benzyl ester ngokubanzi ukwazisa iqela elikhuselayo le-Boc kwiqela le-amino le-glutamic acid, kunye nokwenza i-esterification reaction kunye ne-benzyl anhydride ester kwesi sikhundla. Ukusabela ngokuqhelekileyo kuqhutyelwa phantsi kweemeko ezingathathi hlangothi okanye ezisisiseko kwaye ngokuqhelekileyo kufuna ixesha elithile ukuqinisekisa ukugqitywa kokusabela. Imveliso efunyenweyo inokuhlanjululwa nge-crystallization okanye amanyathelo angaphezulu okucoca.

Ngokuphathelele ulwazi lokhuseleko, ukhuseleko oluthile lwe-Boc-L-Glutamic acid 1-benzyl ester lufuna uphando olongezelelweyo kunye novavanyo. Nangona kunjalo, njengearhente yeekhemikhali, inokuba nokucaphuka okuthile kunye netyhefu. Iinkqubo ezifanelekileyo zelabhoratri mazilandelwe ngexesha lokudibana okanye ukusetyenziswa, kwaye amanyathelo okhuseleko afanelekileyo kufuneka athatyathwe, kubandakanywa ukunxitywa kwezixhobo zokuzikhusela (umz., iiglavu zelebhu, iiglasi zelebhu, njl. njl.). Ngexesha lokusetyenziswa okanye ukulahlwa, inkunkuma kufuneka ilahlwe ngokufanelekileyo ukuphepha ukungcoliseka kwendalo.