BOC-L-Phenylglycine (CAS# 2900-27-8)
| Inkcazelo yoKhuseleko | S22 – Musa ukuphefumla uthuli. S24/25-Kuphephe ukudibana nolusu namehlo. |
| WGK eJamani | 3 |
| Ikhowudi ye-HS | 2924 29 70 |
Intshayelelo
I-N-Boc-L-Phenylglycine yi-organic compound eyenziwa ngokuqulunqwa kwe-chemical bond phakathi kweqela le-amino (NH2) ye-glycine kunye neqela le-carboxyl (COOH) ye-benzoic acid. Isakhiwo sayo siqulethe iqela elikhuselayo (iqela le-Boc), iqela le-tert-butoxycarbonyl, elisetyenziselwa ukukhusela i-reactivity yeqela le-amino.
I-N-Boc-L-phenylglycine inezi mpawu zilandelayo:
- Imbonakalo: Ikristale emhlophe eqinileyo
-Ukunyibilika: Inyibilika kwezinye izinyibilikisi zendalo, njenge dimethylformamide (DMF), dichloromethane, njl.
I-N-Boc-L-phenylglycine isetyenziswa ngokuqhelekileyo kwiimpendulo zamanyathelo amaninzi kwi-organic synthesis, ngokukodwa kwi-synthesis ye-peptide compounds. Iqela elikhuselayo le-Boc linokukhuselwa kwiimeko ze-asidi, ukuze iqela le-amino lisebenze kwaye liqhubele phambili ukuphendula okulandelayo. I-N-Boc-L-phenylglycine nayo ingasetyenziswa njenge-derivative yokwakhiwa kwamaziko e-chiral kwi-peptide synthesis.
Ukulungiswa kwe-N-Boc-L-phenylglycine ikakhulu kuqhutywa ngala manyathelo alandelayo:
I-Glycine i-esterified kunye ne-benzoic acid ukufumana i-benzoic acid-glycinate ester.
Ukusebenzisa i-lithium borotrimethyl ether (i-LiTMP) i-reaction, i-benzoic acid-glycinate ester yayiprotonated kwaye yasabela nge-Boc-Cl (tert-butoxycarbonyl chloride) ukufumana i-N-Boc-L-phenylglycine.
- I-N-Boc-L-phenylglycine inokucaphukisa amehlo, ulusu, kunye nemigudu yokuphefumula kwaye kufuneka igwenywe ngexesha lokusetyenziswa.
- Izixhobo zokukhusela zomntu ezifana neiglavu zelabhoratri, iiglasi zokhuseleko, njl.njl kufuneka zigqitywe ngexesha lokusebenza.
- Kufuneka yenziwe kwindawo yebhubhoratri enomoya omhle.
• Kuphephe ukudibana nee-oxidants kunye neeasidi ezomeleleyo xa ugcina.
- Ukuba uginyiwe okanye uphefumlelwe, funa unyango ngokukhawuleza, uze nesitya sekhompawundi, kwaye unike ulwazi oluyimfuneko lokhuseleko kugqirha.
