I-Boc-L-Tyrosine methyl ester (CAS# 4326-36-7)

Intshayelelo

I-N-Boc-L-Tyrosine i-Methyl Ester yikhemikhali ebizwa ngokuba yi-N-tert-butoxycarbonyl-L-tyrosine methyl ester. Iimpawu zayo zezi zilandelayo:

1. Imbonakalo: emhlophe ukuya kwengwevu yikristale eqinileyo;

5. I-Solubility: i-soluble kwi-solvents ye-organic efana ne-ethanol kunye ne-dimethylformamide (DMF), i-soluble emanzini.

I-N-Boc-L-tyrosine methyl ester isetyenziswa ngokuqhelekileyo kwi-organic synthesis ukukhusela i-amino acids kwi-synthesis ye-polypeptide compounds. Isetyenziswa ngokuqhelekileyo njengeqela elikhuselayo le-L-tyrosine ukukhusela ukusabela okungeyonto ethile ekuphenduleni ukuba kwenzeke. Emva kokuba impendulo igqityiwe, iqela elikhuselayo linokususwa phantsi kweemeko ezifanelekileyo ukufumana imveliso ekujoliswe kuyo.

Indlela yokulungiselela i-N-Boc-L-tyrosine methyl ester idla ngokubandakanya la manyathelo alandelayo:

1. Dissolve L-tyrosine kwi-dimethylformamide (DMF);

2. Yongeza i-sodium carbonate ukuze unciphise iqela le-carboxyl ye-tyrosine;

3. I-Methanol kunye ne-methyl carbonate (i-MeOCOCl) yongezwa kumxube wokuphendula ukuvelisa i-N-Boc-L-tyrosine methyl ester. Ukusabela ngokuqhelekileyo kuqhutyelwa kumaqondo aphantsi, kwaye ukugqithisa kwe-methyl carbonate kusetyenziswa ukuqinisekisa ukuba ukusabela kuyaqhubeka.

I-N-Boc-L-tyrosine methyl ester izinzile, kodwa isafuna ukuphathwa ngononophelo. Oku kulandelayo lulwazi lokhuseleko ngokubanzi:

1. Gwema ukudibanisa nolusu kunye namehlo: Iiglavu ezifanelekileyo zokukhusela kunye neeglavu kufuneka zifakwe ukuphepha ukudibanisa ngokuthe ngqo kunye ne-compound;

2. Gwema ukuphefumla: Ukungena komoya okulungileyo kufuneka kuqinisekiswe kwindawo yokusebenza ukuthintela ukuphefumla kweegesi ezixubileyo;

3. Ukugcinwa: Kufuneka kugcinwe kwindawo epholileyo, eyomileyo kwaye kuphephe ukudibana neoksijini, iiasidi ezinamandla, okanye iziseko ezomeleleyo.

Ngokubanzi, i-N-Boc-L-tyrosine methyl ester yinto ebalulekileyo ephakathi kwi-organic synthesis kwaye idlala indima ebalulekileyo kwi-synthesis ye-peptide compounds. Kufuneka kuthathelwe ingqalelo ukusebenza ngokukhuselekileyo xa usebenzisa naxa uphathwa.