Carbobenzyloxy-beta-alanine (CAS# 2304-94-1)
| Iimpawu ezinobungozi | Xn – Iyingozi |
| Iikhowudi zoMngcipheko | I-R22 – Iyingozi xa iginyiwe I-R41 – Umngcipheko womonakalo omkhulu emehlweni |
| Inkcazelo yoKhuseleko | S26 – Xa udibana namehlo, hlambulula ngokukhawuleza ngamanzi amaninzi kwaye ufune iingcebiso zonyango. S39 –Nxiba ukhuseleko lwamehlo / ubuso. |
| WGK eJamani | 2 |
| Ikhowudi ye-HS | 29242990 |
| IKlasi yeeNgozi | OKUTHUMEKAYO |
Intshayelelo
I-organic compound apho iqela le-carboxyl (-COOH) kwi-molecule ye-alanine kwisakhiwo sele ithathelwe indawo yi-benzyloxycarbonyl (-Cbz) iqela.
Iipropati zekhompawundi:
-Imbonakalo: Umgubo wekristale omhlophe
-Ifomula yemolekyuli: C12H13NO4
-Ubunzima bemolekyuli: 235.24g / mol
-Indawo yokunyibilika: 156-160 ° C
Ezona zinto zisetyenziswayo zezi zilandelayo:
-Kwintsimi ye-organic synthesis, ingasetyenziselwa njengento ephakathi kwi-synthesis yezinye izinto eziyinkimbinkimbi zezinto eziphilayo.
-Njengeqela elikhuselayo leziyobisi ze-polypeptide zokwenziwa, lisetyenziselwa ukukhusela iintsalela ze-alanine.
-Kuphando kunye nokulungiselela ezinye iimolekyuli eziphilayo.
Indlela yokulungiselela inokohlulwa ngokubanzi ibe ngamanyathelo alandelayo:
1. Ukusabela kwe-benzyl chlorocarbamate kunye ne-sodium carbonate ukufumana i-benzyl N-CBZ-methylcarbamate (N-benzyloxycarbonylmethylaminoformate).
2. Phendula imveliso efunyenwe kwisinyathelo sangaphambili kunye nesisombululo se-sodium hydroxide ukufumana i-N-CBZ-β-alanine.
Malunga nolwazi lokhuseleko:
-ukugqithisa ngokuqhelekileyo kuthathwa njengento ekhuselekileyo, kodwa amanyathelo okusebenza afanelekileyo asafuneka.
-Kuphephe ukudibana nolusu, amehlo kunye nomlomo ngexesha lokusetyenziswa.
-Nxiba iiglavu ezifanelekileyo zokukhusela, iiglasi, kunye needyasi zelebhu xa usenza umfuniselo.
-Kuphephe ukuphefumla uthuli olusuka kwikhompawundi.
-I-compound kufuneka igcinwe kwindawo eyomileyo, epholileyo, kwaye ihlukaniswe kwizinto ezinokutsha, i-oxidants kunye nezinye izinto.
Kufuneka kuqatshelwe ukuba ulwazi olunikeziweyo apha lwenzelwe ireferensi kuphela, kwaye incwadana yovavanyo efanelekileyo kunye nephepha ledatha yokhuseleko lwekhemikhali kufuneka kudityanwe nayo phambi kokuba kusetyenziswe ikhompawundi, kwaye ngokuhambelana ngqongqo nemigaqo yokhuseleko lwasebhubhoratri yokusebenza.
