CBZ-D-ALLO-ILE-OH（CAS# 55723-45-0)

Intshayelelo

ZD-allo-Ile-OH . I-DCHA (ZD-allo-Ile-OH · DCHA) i-organic compound kunye ne-reagent yokukhusela i-amino acids. Oku kulandelayo yinkcazo yobume bayo, ukusetyenziswa, ukuqulunqwa kunye nolwazi lokhuseleko:

Indalo:

-Ifomula yeMichiza: C23H31NO5

-Ubunzima bemolekyuli: 405.50g / mol

-Imbonakalo: Ikristale emhlophe eqinileyo

-Indawo yokunyibilika: 105-108°C

-I-Solubility: I-Soluble kwii-solvents eziphilayo ezifana ne-acetone, i-ether, i-dichloromethane, i-insoluble emanzini.

Sebenzisa:

- ZD-allo-Ile-OH . I-DCHA yi-reagent esetyenziselwa ukukhusela i-amino acids. Ngokuzisa iqela le-Cbz kwiqela le-amino le-amino acid, ukuguqulwa ngengozi kweqela le-amino kwindlela yokusabela kwi-chemical synthesis kunokuthintelwa.

-Ihlala isetyenziswa kwi-peptide synthesis, ngakumbi kwi-synthesis yolandelelwano lwe-peptide kunye nezakhiwo ezikhethekileyo okanye imisebenzi.

Indlela yokulungiselela:

- ZD-allo-Ile-OH. Ukulungiswa kwe-DCHA ngokuqhelekileyo kuqala kwi-D-isoleucine, kwaye emva koko isabela nge-Cbz anhydride ye-esterification ukwazisa iqela elikhuselayo le-Cbz. Ekugqibeleni, i-DCHA (i-dichloroformic acid) iphendulwa kunye ne-amino acid ukwenza ityuwa ehambelanayo.

Ulwazi ngoKhuseleko:

- ZD-allo-Ile-OH . I-DCHA ayinayo ityhefu encinci, kodwa kufuneka iphathwe ngononophelo. Kuphephe ukudibana nolusu kunye namehlo, nxiba iiglavu zokhuselo kunye neeglasi ukuba kuyimfuneko.

-Ngexesha lokusetyenziswa, iinkqubo eziqhelekileyo zokusebenza kwebhubhoratri kufuneka zilandelwe kwaye izixhobo ezifanelekileyo zokungenisa umoya kufuneka zisetyenziswe.

-Xa ugcina, gcina i-compound kwindawo eyomileyo, epholileyo kude nemithombo yomlilo kunye namadangatye avulekileyo.