D-1-N-Boc-prolinamide (CAS# 35150-07-3)
| Iimpawu ezinobungozi | Xn – Iyingozi |
| Iikhowudi zoMngcipheko | 22 – Iyingozi xa iginyiwe |
| Inkcazelo yoKhuseleko | 24/25-Kuphephe ukudibana nolusu kunye namehlo. |
| WGK eJamani | 2 |
Intshayelelo
I-D-1-N-Boc-prolinamide(D-1-N-Boc-prolinamide) yi-organic compound eneempawu ezilandelayo:
1. Imbonakalo: Ikristale emhlophe eqinileyo.
2. ifomula yemolekyuli: C14H24N2O3.
3. Ubunzima bemolekyuli: 268.35g/mol.
4. indawo yokunyibilika: malunga ne-75-77 degrees Celsius.
5. Ukunyibilika: Inyibilika emanzini kunye nezinye izinyibilikisi eziphilayo, ezifana chloroform, ethanol kunye dimethyl sulfoxide.
Enye yezona zinto zisetyenziswayo eziphambili ze-D-1-N-Boc-prolinamide njenge-reagent ye-chiral ye-asymmetric synthesis kwi-organic chemical synthesis. Ingasetyenziswa njengebhloko yokwakha ye-chiral skeleton ukwazisa ulwazi lwe-chiral ngeziko le-chiral, ngaloo ndlela ifumana iikhompawundi ze-chiral. Ukongeza, inokuthi isetyenziswe njengendawo ephakathi kwi-synthesis yamachiza, i-pesticides kunye ne-bioactive molekyuli.
Indlela yokulungiselela i-D-1-N-Boc-prolinamide idla ngokusabela i-N-Boc-L-proline kunye ne-tert-butyl chloroformate phantsi kweemeko ze-alkali ukuvelisa i-N-Boc-L-proline methyl ester ephakathi, kwaye emva koko unyango lobushushu ukuvelisa imveliso ekujoliswe kuyo.
Ngokumalunga nolwazi lokhuseleko, izifundo ezineenkcukacha ze-toxicological zinqongophele i-D-1-N-Boc-prolinamide. Nangona kunjalo, ngokubanzi, imisebenzi yokhuseleko lwebhubhoratri yesiqhelo kufuneka ilandelwe, kwaye amanyathelo okukhusela afana neeglavu, izibuko kunye nempahla yokukhusela kufuneka inikwe ingqalelo xa usebenzisa. Ukongezelela, kufuneka igcinwe kwisitya esivaliweyo ukuze ugweme ukudibanisa ne-oxygen kunye nomswakama. Ukuba uphefumle ngempazamo okanye udibane nolusu kunye namehlo, hlambulula ngokukhawuleza ngamanzi amaninzi kwaye ufune uncedo lwezonyango. Ukuba inkunkuma kufuneka ilahlwe, imigaqo yendawo kufuneka ilandelwe. Kungcono ukusebenzisa kunye nokuphatha ikhompawundi phantsi kwesikhokelo somntu onemvelaphi yobuchwephesha kwikhemistri.
