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D-Glutamine (CAS # 5959-95-5) Umfanekiso obonakalayo
  • D-Glutamine (CAS# 5959-95-5) 1

D-Glutamine (CAS# 5959-95-5)

Ipropati yeMichiza:

Ifomula yeemolekyuli C5 H10 N2 O3
IMisa yeMolar 146.14
Ukuxinana 1.3394 (uqikelelo olurhabaxa)
Indawo yokunyibilika 184-185 °C
Indawo yeBoling 265.74°C (uqikelelo olurhabaxa)
Ujikelezo oluthile(α) -32 º (589nm, c=10, N HCl)
Ukunyibilika kwamanzi 42.53g/L(iqondo lobushushu alichazwanga)
Ukunyibilika Inyibilika emanzini (9 mg/ml kwi-25 °C), i-DMSO (<1 mg/ml kwi-25 °C), kunye ne-ethanol (<1 mg/m
Imbonakalo Umgubo omhlophe wekristale
Umbala Mhlophe
I-BRN 1723796
pKa 2.27±0.10(Kuqikelelwe)
Imeko yoGcino Gcina kwindawo emnyama, umoya ongena ngaphakathi, ubushushu begumbi
Refractive Index -33 ° (C=5, 5mol/LH
MDL MFCD00065607
IiPropati zoMzimba kunye nezeMichiza Indawo enyibilikayo: 185
Isifundo se-in vitro I-Glutamine ingundoqo ye-amino acid kwinkqubo ye-nervous central (CNS), idlala indima ebalulekileyo kumjikelezo we-glutamate / GABA-Glutamine (GGC). Kwi-GGC, i-Glutamine ikhutshelwa ukusuka kwi-astrocyte ukuya kwi-neurons, apho iya kuzalisa amachibi athintelayo kunye ne-excitatory neurotransmitter. I-D-Glutamine isetyenziselwe ukufunda indima yayo ekunikezeni ukhuseleko ngokuchasene ne-acetaldehyde-induced disruption of barrier function in Caco-2 cell monolayer. Indima ye-L-Glutamine ekukhuselweni kwe-epithelium yamathumbu ukusuka kwi-acetaldehyde-induced disruption of barrier function ivandlakanywa kwiCaco-2 cell monolayer. I-L-Glutamine yanciphisa ukuhla kwe-acetaldehyde-induced induction in transepithelilal resistance resistance and increase in permeability to inulin and lipopolysaccharide in a time-and-dependent-dependent form; I-D-Glutamine, i-L-aspargine, i-L-arginine, i-L-lysine, okanye i-L-alanine ivelise ukhuseleko olubalulekileyo. I-D-Glutamine nayo iyasilela ukuchaphazela ukuhla kwe-acetaldehyde-induced in TER kunye nokwanda kwe-inulin flux. I-D-Glutamine okanye i-glutaminase inhibitor ngokwayo ayizange ichaphazele i-TER okanye i-inulin flux ekulawuleni okanye i-acetaldehyde-treated cell monolayers. Ukungabikho kwempembelelo ye-D-Glutamine ekukhuseleni kwi-acetaldehyde ibonisa ukuba ukhuseleko lwe-L-Glutamine-mediated luyi-stereospecific.

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Iithegi zeMveliso

Iimpawu ezinobungozi Xi – Irritant
Iikhowudi zoMngcipheko 36/37/38 – Ukucaphukisa amehlo, inkqubo yokuphefumula kunye nolusu.
Inkcazelo yoKhuseleko S36/37/39 – Nxiba iimpahla ezifanelekileyo zokukhusela, iiglavu kunye nokukhusela amehlo/ubuso.
S26 – Xa udibana namehlo, hlambulula ngokukhawuleza ngamanzi amaninzi kwaye ufune iingcebiso zonyango.
S27 – Khulula ngoko nangoko zonke iimpahla ezosulelekileyo.
S24/25-Kuphephe ukudibana nolusu namehlo.
WGK eJamani 3
Ikhowudi ye-HS 29241900

 

Intshayelelo

Isomeri engeyondalo yeglutamine ayinyibiliki kwi-methanol, ethanol, ether kunye nebenzene.

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