Ethyl L-pyroglutamate (CAS# 7149-65-7)

Ifomula yeemolekyuli	C7H11NO3
IMisa yeMolar	157.17
Ukuxinana	1.2483 (uqikelelo olurhabaxa)
Indawo yokunyibilika	54-56°C
Indawo yeBoling	176°C12mm Hg(lit.)
Ujikelezo oluthile(α)	-3.5 º (c=5, amanzi)
Indawo yokuflasha	>230°F
Imbonakalo	Ukunyibilika okuphantsi okuqinileyo
Umbala	Emhlophe ukuya kwikhilimu
I-BRN	82621
pKa	14.78±0.40(Kuxelwe kwangaphambili)
Imeko yoGcino	Gcina kwindawo emnyama, itywinwe kwindawo eyomileyo, ubushushu beGumbi
Refractive Index	1.4310 (uqikelelo)
MDL	MFCD00064497

Iinkcukacha zeMveliso

Iimpawu ezinobungozi	Xi – Irritant
Iikhowudi zoMngcipheko	36/37/38 – Ukucaphukisa amehlo, inkqubo yokuphefumula kunye nolusu.
Inkcazelo yoKhuseleko	S26 – Xa udibana namehlo, hlambulula ngokukhawuleza ngamanzi amaninzi kwaye ufune iingcebiso zonyango. S36 – Nxiba iimpahla ezifanelekileyo ezikhuselayo. I-S37/39 -Nxiba iiglavu ezifanelekileyo kunye nokukhusela amehlo / ubuso
WGK eJamani	3
FLUKA BRAND F IIKHOWUDI	3-10
Ikhowudi ye-HS	29339900

Intshayelelo	I-ethyl L-pyroglutamate imhlophe ukuya kumbala okhilimu omhlophe, ophantsi onyibilikayo oqinileyo ophuma kwi-amino acid engeyiyo yendalo, i-amino acids engekho ngokwemvelo isetyenziswe kwiibhaktheriya, igwele kunye neeseli ze-mammalian zokuguqulwa kweprotheni, eziye zasetyenziswa kuphando olusisiseko kunye neyeza. uphuhliso, ubunjineli bebhayoloji kunye neminye imimandla, isetyenziswa kakhulu ukubona utshintsho lweprotheyini yesakhiwo, ukudibanisa iziyobisi, ii-biosensors njalo njalo.
Sebenzisa	I-ethyl L-pyroglutamate ingasetyenziswa njengeemolekyuli ezixutywe ngamayeza kunye neziphakathi kwi-organic synthesis, umzekelo, iimolekyuli zokwenziwa zebhayoloji ezisebenzayo ezifana ne-HIV integrase inhibitors. Kuguqulo lokwenziwa, i-athomu yenitrogen kwiqela le-amide inokudityaniswa ne-iodobenzene, kwaye i-hydrogen kwi-athomu ye-nitrogen inokuguqulwa ibe yi-athomu ye-chlorine. Ukongeza, iqela le-ester linokuguqulwa libe yimveliso ye-amide ngokuphendula kwe-urethane.
indlela yokwenziwa	yongeza I-L-pyroglutamic acid (5.00g), i-P-toluenesulfonic acid monohydrate (369 mg, 1.94 mmol) kunye ne-ethanol (100) mL) zixutywe ubusuku bonke kwiqondo lokushisa, i-residu yachithwa kwi-500 EtOAc, isisombululo saxutywa nge-potassium carbonate kwaye (emva kokuhluzwa), i-organic layer yomiswa ngaphezulu. I-MgSO4, kunye nesigaba se-organic sigxininiswe kwi-vacuo ukunika i-ethyl L-pyroglutamate. Umzobo we-1 ukuhlanganiswa kwe-ethyl L-pyroglutamate