Fmoc-11-Aminoundecanoic acid (CAS# 88574-07-6)
| Iimpawu ezinobungozi | Xi – Irritant |
| Iikhowudi zoMngcipheko | 36/37/38 – Ukucaphukisa amehlo, inkqubo yokuphefumula kunye nolusu. |
| Inkcazelo yoKhuseleko | S26 – Xa udibana namehlo, hlambulula ngokukhawuleza ngamanzi amaninzi kwaye ufune iingcebiso zonyango. S36 – Nxiba iimpahla ezifanelekileyo ezikhuselayo. |
| WGK eJamani | 3 |
| IKlasi yeeNgozi | OKUTHUMEKAYO |
Intshayelelo
I-11- (FMOC-amino) i-undecanoic acid, eyaziwa ngokuba yi-FMOC-11-AMINOUNDECANOIC ACID. Oku kulandelayo sintshayelelo kubume bayo, ukusetyenziswa, iindlela zokwenza kunye nolwazi lokhuseleko:
Umgangatho:
- Imbonakalo: 11-(FMOC-amino) i-undecanoic acid yikristale eqinileyo emhlophe.
- Ukunyibilika: Inokunyibilika kwezinye izinyibilikisi eziphilayo ezifana nekloroform, i-dimethyl sulfoxide, kunye ne-methylene chloride, kodwa i-solubility encinci emanzini.
Sebenzisa:
- Uphando lwe-Biochemical: 11- (FMOC-amino) i-undecanoic acid isetyenziswa ngokuqhelekileyo njengento ekhuselayo kunye ne-activator kwi-peptide synthesis kunye nophando.
- Uhlalutyo lwemichiza: Ingasetyenziswa njengomgangatho oqhelekileyo okanye wangaphakathi kuhlalutyo lwe-amino acid.
Indlela:
Ukulungiswa kwe-11-(FMOC-amino) undecanoic acid inokuqhutywa ngala manyathelo alandelayo:
- Hlanganisa i-11-aminoundecanoic acid kunye ne-dioxins kunye ne-tetrahydrofurans kwaye ngokuthe ngcembe wongeze i-trichlorotrimethylphosphoketone (TMSCl) ngelixa upholisa kwaye uvuselela.
- Emva koko fudumeza umxube kwiqondo lobushushu begumbi phambi kokuba wongeze i-trifluoromethanesulfonic acid (TfOH).
- I-N-(9-fluoroformyl) isisombululo se-morphine amide ester yongezwa, kwaye emva kokusabela kunye nokucocwa, imveliso ecocekileyo yafunyanwa.
Ulwazi ngoKhuseleko:
Ulwazi lokhuseleko malunga ne-11-(FMOC-amino) i-undecanoic acid okwangoku ayifane ixelwe, kodwa imiqathango yokuphathwa kwelabhoratri yesiqhelo kunye nokusetyenziswa kweekhemikhali kufuneka ilandelwe. Nxiba izixhobo ezifanelekileyo zokuzikhusela xa usebenzisa, kuphephe ukudibana nolusu namehlo, kwaye uqinisekise ukuba uzisebenzisa kwindawo engena umoya. Ukuba kuyimfuneko, nceda ubhekisele kwiPhepha leDatha loKhuseleko elifanelekileyo (SDS) ngolwazi oluthe vetshe ngokhuseleko.
