Fmoc-2-Amino-2-methylpropionic acid (CAS# 94744-50-0)

Intshayelelo

I-Fmoc-2-aminoisobutyric acid, eyaziwa ngokuba yi-Fmoc-Aib, i-organic compound. Oku kulandelayo yintshayelelo eneenkcukacha kwezinye iipropati, ukusetyenziswa, iindlela zokulungiselela kunye nolwazi lokhuseleko lwe-Fmoc-2-aminoisobutyric acid:

Umgangatho:

I-Fmoc-2-aminoisobutyric acid yikristale emhlophe eqinileyo enevumba elikhethekileyo. Izinzile kwiqondo lokushisa kwaye ayinyibiliki emanzini, kodwa i-soluble kwi-organic solvents efana ne-methanol kunye ne-methylene chloride.

Sebenzisa:

I-Fmoc-2-aminoisobutyric acid liqela elisetyenziswa ngokuqhelekileyo elikhuselayo kwi-organic synthesis. Ingasetyenziswa njengeqela ukukhuselwa okwethutyana amaqela amino kwi polypeptides zokwenziwa kunye neeproteni ukuthintela reactions icala kwi reactions imichiza.

Indlela:

Indlela yokulungiselela i-FOC-2-aminoisobutyric acid ngokuqhelekileyo yi-chemical synthesis. Oku ngokuqhelekileyo kwenziwa ngokusabela kwe-2-aminoisobutyric acid kunye ne-Fmoc-OSu (Fmoc-N-hydroxysuccinimidyl) okanye i-Fmoc-OXy (Fmoc-N-hydroxysuccinimidate). Ukusabela ngokuqhelekileyo kuqhutyelwa kwiqondo lokushisa legumbi kwaye lihlanjululwe ngokutsalwa kwe-solvent kunye ne-crystallization.

Ulwazi ngoKhuseleko:

I-FMOC-2-aminoisobutyric acid ikhuselekile ngokubanzi phantsi kweemeko eziqhelekileyo zokusetyenziswa. Njengomxube wezinto eziphilayo, inokubangela umngcipheko othile kwimpilo yabantu. Ukunyamekela kufuneka kuthathwe ukuphepha ukuphefumla umgubo okanye izisombululo ngelixa uthintela ukudibanisa nolusu kunye namehlo. Iiglavu ezikhuselayo, iiglasi, kunye nemaski kufuneka zinxitywe xa kuyimfuneko. Xa udibana nesikhumba okanye amehlo, hlambulula ngokukhawuleza ngamanzi amaninzi kwaye ufune unyango. Kufuneka igcinwe kwindawo eyomileyo, epholileyo, kude nomlilo kunye ne-oxidants.