Fmoc-D-2-Aminobutyric acid (CAS# 170642-27-0)

I-Fmoc-D-Abu-OH yi-D-elungiselelwe i-2-aminobutyric acid derivative. Ngumgubo oqinileyo, omhlophe ukuya kumthubi okhanyayo ngombala. Oku kulandelayo yinkcazo yohlobo, ukusetyenziswa, ukulungiswa kunye nolwazi lokhuseleko lwe-Fmoc-D-Abu-OH:Indalo:
I-Fmoc-D-Abu-OH inokunyibilika okulungileyo kwaye iyanyibilika kwizinyibilikisi zezinto eziphilayo ezifana ne-dimethylformamide (DMF) kunye neklorofomu. Indawo yayo yokunyibilika yi-130-133 degrees Celsius.

Sebenzisa:
I-Fmoc-D-Abu-OH iqhele ukusetyenziswa kwi-peptide synthesis kwi-slide phase synthesis njengesixhobo esibalulekileyo sokukhusela idipeptide. Ingasetyenziselwa njenge-activator ye-synthesis ye-polypeptides kunye ne-peptide compounds.

Indlela:
I-Fmoc-D-Abu-OH ilungiswa ngokubanzi yi-Fmoc ekhusela iqela le-hydroxyl ye-D-2-aminobutyric acid, kwaye yenza i-Fmoc-D-Abu-OH ngokusabela okufanelekileyo.

Ulwazi ngoKhuseleko:
I-Fmoc-D-Abu-OH yimichiza kwaye kufuneka iphathwe ngokuhambelana neenkqubo zokusebenza ezikhuselekileyo. Inokuba neziphumo ezicaphukisayo emehlweni, ulusu kunye nephecana lokuphefumla, ngoko ke kuyimfuneko ukunxiba izixhobo ezifanelekileyo zokuzikhusela, ezinjengeiglavu zaselabhoratri, iiglasi kunye neemaski zokhuselo. Gwema ukudibana nee-oxidants ezinamandla kunye ne-acids ezomeleleyo ngexesha lokusetyenziswa kunye nokugcinwa ukukhusela ukuphendula okuyingozi. Kwimeko yokuphefumla, ukudibana kwesikhumba okanye ukudibana kwamehlo, hlambulula ngokukhawuleza ngamanzi kwaye ufune uncedo lwezonyango.