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I-Fmoc-D-3-Cyclohexyl Alanine (CAS# 144701-25-7)

Ipropati yeMichiza:

Ifomula yeemolekyuli C24H27NO4
IMisa yeMolar 393.48
Ukuxinana 1.209±0.06 g/cm3(Kuxelwe kwangaphambili)
Indawo yeBoling 610.5±38.0 °C(Kuqikelelwe)
Indawo yokuflasha 323°C
Uxinzelelo loMphunga 9.3E-16mmHg ku-25°C
Imbonakalo Umgubo
Umbala Mhlophe
pKa 3.91±0.10(Kuqikelelwe)
Imeko yoGcino Itywinwe kwindawo eyomileyo,2-8°C

Iinkcukacha zeMveliso

Iithegi zeMveliso

Umngcipheko kunye noKhuseleko

Inkcazelo yoKhuseleko S22 – Musa ukuphefumla uthuli.
S24/25-Kuphephe ukudibana nolusu namehlo.
WGK eJamani 3
FLUKA BRAND F IIKHOWUDI 10
Ikhowudi ye-HS 2924 29 70
IKlasi yeeNgozi OKUTHUMEKAYO

Intshayelelo

I-Fmoc-D-3-Cyclohexyl Alanine (i-CAS # 144701-25-7), edla ngokubizwa ngokuba yi-Fmoc-D-amino acid, i-organic compound. Ifunyenwe ngokongeza iqela le-methoxycarbonyl kwiqela le-amino le-fmoc-3-cyclohexyl-D-alanine.

Ngokubhekiselele kwiipropati ze-FMOC-D-amino acid, isisombululo esiqinileyo okanye esicacileyo esinokuchithwa kwezinye i-solvents eziphilayo, ezifana ne-dimethyl sulfoxide (DMSO) kunye ne-methanol (MeOH). Ineempawu ezinamandla zokufunxa i-UV, ebonisa ukufunxa okuphezulu kuluhlu lwe-240-245 nm.

I-FMOC-D-amino acid inoluhlu olubanzi lwezicelo kuphando lwe-biochemical. Enye yezona zinto ziqhelekileyo zokusetyenziswa njengeqela elikhuselayo le-solid-phase synthetase peptides kunye ne-polypeptides, ukukhusela i-hydroxyl okanye amaqela e-amino ngexesha lokudibanisa. Ukongeza, ingasetyenziselwa ukuhlanganiswa kweekhompawundi ze-steroid ezisebenzayo kunye nokulungiswa kweepeptides okanye iiprotheni zolandelelwano oluthile.

Indlela eqhelekileyo yokulungiselela i-FMOC-D-amino acid kukongeza i-FMOC chlorinating reagent kwiqela le-amino le-fmoc-3-cyclohexyl-D-alanine, kwaye uqhube ukusabela kwi-solvent efanelekileyo kunye neemeko zokusabela. Emva koko, imveliso efunwayo inokufunyanwa ngamanyathelo afanelekileyo okucoca afana ne-solvent extraction kunye nekholamu yechromatography.

Ngokuphathelele ulwazi lokhuseleko, i-FOC-D-amino acids ikhuselekile ngokufanelekileyo phantsi kweemeko zokusebenza ngokubanzi. Nangona kunjalo, kusafuneka kuthathwe amanyathelo afanelekileyo okhuseleko aselabhoratri, anjengokunxiba izixhobo ezifanelekileyo zokuzikhusela nokusebenza kwindawo engenamoya eyaneleyo. Ukongezelela, ngokwemiqathango ethile yebhubhoratri nganye, iinkqubo ezifanelekileyo zokusebenza zokhuseleko kunye nezilumkiso kufuneka zilandelwe ngexesha lokusetyenziswa kunye nokuphathwa.

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