Fmoc-D-Cyclohexyl glycine (CAS# 198543-96-3)
Iinkcukacha zeMveliso
Iithegi zeMveliso
Umngcipheko kunye noKhuseleko
| IKlasi yeeNgozi | OKUTHUMEKAYO |
Fmoc-D-Cyclohexyl glycine (CAS# 198543-96-3) Ulwazi
| Sebenzisa | I-Fluorene methoxycarbonyl D-cyclohexylglycine yinto eqhelekileyo yokuxuba kunye neekhemikhali eziphakathi, i-fluorenyl chloride (FMOC-Cl) yi-chloroformate. Isetyenziselwa ukwenza i-fluorene methoxycarbonyl (iqela le-FMOC) ibe yi-fluorene methoxycarbonyl carbamate FMOC carbamate, liqela eliqhelekileyo lokukhusela i-amino. |
| Ukulungiselela | Ukwenziwa kwe-fluorene methoxycarbonyl D-cyclohexylglycine kuye kwabikwa kwiincwadi. Ukusebenzisa i-cyclohexyl bromide njengento eluhlaza, phambi kwe-sodium alkoxide, ifumana i-alkylation reaction kunye ne-diethyl malonate, kwaye emva koko i-hydrolyzes, i-acidifies, kunye ne-decarboxylates ukufumana i-cyclohexyl acetic acid; le yokugqibela ke brominated kunye ammonolysis DL-Cyclohexylglycine; Ekugqibeleni, ukusabela kwe-acylation kwenzeka kubukho be-fluorene methoxycarbonyl chloride ukufumana i-fluorene methoxycarbonyl D-cyclohexylglycine [1]. Indlela yokusabela yokudibanisa imi ngolu hlobo lulandelayo: |
Ngaphambili: AC-TYR-NH2 (CAS# 1948-71-6) Okulandelayo: 2-Amino-4-bromobenzoic acid (CAS# 20776-50-5)
