FMOC-D-Valine (CAS# 84624-17-9)
| Inkcazelo yoKhuseleko | S22 – Musa ukuphefumla uthuli. S24/25-Kuphephe ukudibana nolusu namehlo. |
| WGK eJamani | 3 |
| Ikhowudi ye-HS | 2924 29 70 |
Intshayelelo
I-fmoc-D-valine(fmoc-D-valine) sisixhobo sokuvuselela iikhemikhali ikakhulu sisetyenziswa kwi-peptide synthesis kunye nobunjineli beprotheyini kwisigaba esiluqilima. Inezi mpawu zilandelayo:
1. Iimpawu zeekhemikhali: i-fmoc-D-valine iqinile emhlophe, ene-hydrophobic. Iyanyibilika kwii-solvents eziphilayo ezifana ne-dimethyl sulfoxide (DMSO) kunye ne-methylene chloride, kodwa ayinyibiliki kakuhle emanzini. Ifomula yayo ye-molecular yi-C21H23NO5 kunye nobunzima bayo be-molecular yi-369.41.
2. sebenzisa: i-fmoc-D-valine yenye yezinto ezibalulekileyo zokwenziwa kwe-peptides kunye neeprotheni, zingasetyenziselwa ukuhlanganiswa kweepeptides ezisebenzayo. Iqhele ukusetyenziswa kwi-slid-phase synthesis ukwenza amatyathanga e-peptide ngokusabela kwe-condensation kunye nezinye iintsalela ze-amino acid. Ukongeza, inokusetyenziselwa ukufunda ukuhlanganiswa kweepeptides ezisebenzayo kunye noyilo lwamachiza.
3. Indlela yokulungiselela: I-synthesis ye-fmoc-D-valine idla ngokuqhutyelwa yi-chemical synthesis method. I-L-valine iqala ukusabela kunye neqela elikhuselayo le-Fmoc ukukhusela iqela le-amino kwi-chemical reaction. Iqela elikhuselayo le-Fmoc liye lisuswe yi-deprotection reaction ukunika i-fmoc-D-valine.
4. ulwazi lokhuseleko: i-fmoc-D-valine inokhuseleko olulungileyo phantsi kweemeko eziqhelekileyo zokusetyenziswa, kodwa kusafuneka ukuba ithathele ingqalelo oku kulandelayo: ukuphepha ukudibana nolusu kunye namehlo, njengokudibana ngengozi, kufuneka uhlambe ngokukhawuleza ngamanzi amaninzi, kwaye ufune uncedo lwezonyango; Ngexesha lokusebenza kufuneka ingqalelo kwisondlo kunye nococeko lomntu; ugcino kufuneka luvalwe, kuthintelwe ukukhanya kwelanga kunye nendawo efumileyo. Xa usebenzisa, nceda ubhekisele kwimiyalelo yokhuseleko efanelekileyo kunye namaxwebhu edatha yokhuseleko lwempahla (MSDS).
