I-Fmoc-L-aspartic acid (CAS# 119062-05-4)

I-Fmoc-L-aspartic acid yi-amino acid ephumayo eneempawu ezilandelayo:

Ukubonakala: umgubo omhlophe okanye omhlophe we-crystalline.
Ukunyibilika: Ukunyibilika okulungileyo kwizinyibilikisi ze-organic (ezifana ne-dimethyl sulfoxide, i-dimethylformamide), kodwa ukunyibilika kakubi emanzini.

I-Fmoc-L-aspartic acid inoluhlu olubanzi lwezicelo kuphando lwe-biochemical kunye ne-organic synthesis, kwaye usetyenziso oluphambili lulandelayo:

I-Peptide synthesis: I-Fmoc-L-aspartic acid idla ngokusetyenziswa kwi-soli-phase synthesis njengenye yeeyunithi ze-amino acid zokwenziwa kweepeptides kunye neeproteni.
Uphando lwebhayoloji: I-Fmoc-L-aspartic acid ingasetyenziselwa ukufunda ubume beprotheyini kunye nokusebenza, okufana nolwakhiwo kunye nobudlelwane bomsebenzi weeproteni ngokwenza amaqhekeza epeptides.

Indlela yokulungiselela i-Fmoc-L-aspartic acid idla ngokufunyanwa yi-chemical reaction ngokusebenzisa i-acetyl-L-aspartic acid kunye ne-Fmoc-Cl (difluorothiophenolate) njengezinto eziluhlaza.

Ulwazi loKhuseleko: I-Fmoc-L-aspartic acid i-reagent eqhelekileyo kwiilabhoratri ze-chemistry, kodwa kufuneka isetyenziswe ngononophelo. Xa usebenza, kuyimfuneko ukunxiba iiglavu zaselabhoratri, iiglasi ezikhuselayo, kunye nempahla yaselabhoratri ukuphepha ukunxibelelana ngokuthe ngqo nolusu kunye namehlo. Kwakhona, qaphela ukuphepha ukuphefumla umgubo wemveliso ukunqanda ukubangela ukucaphuka kokuphefumula. Kwimeko naziphi na iingozi, uncedo lokuqala olufanelekileyo kufuneka luthathwe ngokukhawuleza kwaye abaqeqeshi bezonyango kufuneka badibane.