Fmoc-L-Serine (CAS# 73724-45-5)
| Iimpawu ezinobungozi | Xi – Irritant |
| Iikhowudi zoMngcipheko | 36/37/38 – Ukucaphukisa amehlo, inkqubo yokuphefumula kunye nolusu. |
| Inkcazelo yoKhuseleko | S22 – Musa ukuphefumla uthuli. S24/25-Kuphephe ukudibana nolusu namehlo. S26 – Xa udibana namehlo, hlambulula ngokukhawuleza ngamanzi amaninzi kwaye ufune iingcebiso zonyango. |
| WGK eJamani | 3 |
| Ikhowudi ye-HS | 29242990 |
Intshayelelo
I-N-Fmoc-L-Serine (i-Fmoc-L-Serine) yimbumba ephilayo esetyenziswa ngokuqhelekileyo kwi-peptide synthesis. Oku kulandelayo yinkcazo yeepropati, ukusetyenziswa, ukulungiswa kunye nolwazi lokhuseleko lwe-N-Fmoc-L-serine:
Indalo:
-Imbonakalo: I-granular emhlophe ukuya kumhlophe okanye i-crystalline powder.
-Ifomula yemolekyuli: C21H21NO5
-Ubunzima bemolekyuli: 371.40g / mol
-Indawo yokunyibilika: malunga ne-100-110 degrees Celsius
Sebenzisa:
- I-Fmoc-L-serine yinto esetyenziswa ngokuqhelekileyo i-serine derivative, enokusetyenziswa kwi-synthesis yesigaba esiqinileyo okanye i-liquid phase synthesis kwintsimi ye-peptide synthesis.
-Ingasetyenziswa njengeqela elikhuselayo kwiintsalela ze-serine ukukhusela iqela le-hydroxyl le-serine ukukhusela ukuphendula okungafunekiyo.
-Kwi-synthesis ye-polypeptides kunye neeprotheni, i-Fmoc-L-serine ingasetyenziselwa ukwakha izakhiwo ze-peptide eziyinkimbinkimbi, kubandakanywa ukuguqulwa kunye nokulawulwa komsebenzi.
Indlela yokulungiselela:
-Ukulungiswa kwe-Fmoc-L-serine kunokufunyanwa ngeendlela zeekhemikhali zokwenziwa. Ngokuqhelekileyo, i-L-serine iqala ukusabela nge-Fmoc-Cl (i-Fmoc chloride) ukwenza i-N-Fmoc-L-serine phantsi kweemeko ezisisiseko.
Ulwazi ngoKhuseleko:
- I-Fmoc-L-Serine yikhemikhali kwaye kufuneka iphathwe ngokuhambelana neenkqubo zokhuseleko lwebhubhoratri.
-Kuphephe ukudibana ngqo nesikhumba kunye namehlo ngexesha lokusebenza ukuphepha ukucaphuka.
-Xa ugcina, gcina i-Fmoc-L-serine kwindawo eyomileyo, epholileyo, kude nomlilo kunye ne-oxidizing agents.
