FMOC-NLE-OH (CAS# 77284-32-3)
| Inkcazelo yoKhuseleko | S22 – Musa ukuphefumla uthuli. S24/25-Kuphephe ukudibana nolusu namehlo. |
| WGK eJamani | 3 |
| Ikhowudi ye-HS | 2924 29 70 |
| IKlasi yeeNgozi | OKUTHUMEKAYO |
Intshayelelo
I-N-Fmoc-L-norleucine (i-Fmoc-L-Norleucine) i-amino acid derivative. Inezi mpawu zilandelayo:
1. Imbonakalo: I-Fmoc-L-norleucine yinto eqinileyo emhlophe ukuya kumthubi.
2. Ukunyibilika: Inyibilika kakuhle kwezinye izinyibilikisi eziphilayo (ezifana ne-methanol, i-dichloromethane kunye ne-dimethylthionamide).
3. Ukuzinza: Ikhompawundi inokugcinwa ngokuzinzileyo ixesha elide kwiqondo lokushisa.
I-Fmoc-L-norleucine inezicelo ezininzi kwi-biochemistry kunye ne-organic synthesis:
1. I-Peptide synthesis: Ihlala isetyenziselwa ukuhlanganiswa kwesigaba esiqinileyo kunye nolwelo lwesigaba se-liquid njengenye yeeyunithi ze-amino acid ekwakheni amatyathanga e-polypeptide.
2. Uphando lweprotheyini: I-Fmoc-L-norleucine ingasetyenziselwa ukufunda ubume beprotheyini kunye nomsebenzi, kunye nophando olunxulumene nobunjineli bemfuza.
3. Uphuhliso lweziyobisi: Ikhompawundi ingasetyenziswa njengento yokuqala ukuyila kunye nokudibanisa abaviwa beziyobisi.
Indlela yokulungiselela i-Fmoc-L-norleucine ngokuqhelekileyo iqondwa nge-organic synthesis. Indlela eqhelekileyo yokwenziwa kukusabela kwe-norleucine kunye ne-Fmoc-carbamate phantsi kweemeko ezisisiseko.
Ngokumalunga nolwazi lokhuseleko, iFmoc-L-norleucine ikhuselekile ngokwentelekiso phantsi kweemeko zokusebenza ngokubanzi, kodwa le miba ilandelayo isafuna ukuqatshelwa:
1. Kulumkele ukudibana nolusu namehlo: Nxiba izixhobo ezifanelekileyo zokuzikhusela, ezinjengeeglavu zaselabhu kunye neglavu.
2. Kuphephe ukuphefumla okanye ukungeniswa: Ukungena komoya okulungileyo kufuneka kuqinisekiswe ngexesha lokusebenza ukuphepha ukuveliswa kothuli. Ukuba uphefumlelwe okanye ukutyile, funa unyango ngokukhawuleza.
3. ukugcinwa kunye nokuphatha: I-Fmoc-L-norleucine kufuneka igcinwe kwindawo eyomileyo, epholileyo, kude nezinto ezinokutsha. Ukulahlwa kwenkunkuma kuya kuhambelana nemigaqo efanelekileyo yokusingqongileyo.
