FMOC-O-tert-Butyl-L-serine (CAS# 71989-33-8)
| Iimpawu ezinobungozi | Xi – Irritant |
| Iikhowudi zoMngcipheko | 36/37/38 – Ukucaphukisa amehlo, inkqubo yokuphefumula kunye nolusu. |
| Inkcazelo yoKhuseleko | S24/25-Kuphephe ukudibana nolusu namehlo. S36/37/39 – Nxiba iimpahla ezifanelekileyo zokukhusela, iiglavu kunye nokukhusela amehlo/ubuso. S27 – Khulula ngoko nangoko zonke iimpahla ezosulelekileyo. S26 – Xa udibana namehlo, hlambulula ngokukhawuleza ngamanzi amaninzi kwaye ufune iingcebiso zonyango. |
| WGK eJamani | 3 |
| Ikhowudi ye-HS | 29242990 |
Intshayelelo
I-FMOC-O-tert-butyl-L-serine yi-organic compound, kwaye igama layo lekhemikhali yi-epichlorotoluene serine. Oku kulandelayo sintshayelelo kwiipropati zayo, ukusetyenziswa, iindlela zokuvelisa kunye nolwazi lokhuseleko:
Umgangatho:
I-FMOC-O-tert-butyl-L-serine iqinile kunye nenkangeleko emhlophe ukuya kumhlophe. Ibola kwisisombululo kwaye iyakwazi ukufuma.
Sebenzisa:
I-FMOC-O-tert-butyl-L-serine liqela elisetyenziswa ngokuqhelekileyo le-aminoprotective elisetyenziswa ngokubanzi kwi-synthesis ye-peptides kunye neeprotheni. Ukusetyenziswa kwayo okuphambili njengeqela elikhuselayo lamatyathanga e-peptide, ngokukhusela amaqela e-amino ngexesha lokudibanisa kunye nokuphepha ukusabela kwabo kunye namanye amaqela asebenzayo. Ikwanayo ne-solubility efanelekileyo kwaye inokusetyenziswa njenge-synthetic intermediate.
Indlela:
Ukulungiswa kwe-FMOC-O-tert-butyl-L-serine ngokuqhelekileyo isebenzisa isicwangciso sokukhusela i-FMOC esidityaniswe ne-reaction ye-Wick. I-Tert-butoxycarbonyl methylserine iphendulwa kunye ne-triethylamine kunye ne-tetraethyl disilicate ukwenza i-FMOC-O-tert-butyl-L-serine. Indlela ethile yokudibanisa kufuneka yenziwe phantsi kweemeko ezifanelekileyo zebhubhoratri.
Ulwazi ngoKhuseleko:
Ukusetyenziswa kwe-FMOC-O-tert-butyl-L-serine kufuneka ilandele iindlela ezikhuselekileyo. Isenokuba nefuthe elicaphukisayo emehlweni, eluswini, nakwindlela yokuphefumla ngendlela ecocekileyo. Izixhobo ezifanelekileyo zokukhusela ezinjengeeglavu, iiglasi zokhuseleko, kunye nezixhobo zokukhusela ukuphefumla kufuneka zinxitywe xa zisetyenziswa. Kufuneka igcinwe kude namadangatye avulekileyo kunye nemithombo yobushushu kwaye iqhutywe kwindawo engena umoya. Ukuba utyiwe okanye urholile, funa unyango ngokukhawuleza.
