Ifowuni: +86 21 6460 6569
iphepha_ibhena

imveliso

Fmoc-O-tert-butyl-L-tyrosine (CAS# 71989-38-3) Umfanekiso okhoyo
  • Fmoc-O-tert-butyl-L-tyrosine (CAS# 71989-38-3) 1

Fmoc-O-tert-butyl-L-tyrosine (CAS# 71989-38-3)

Ipropati yeMichiza:

Ifomula yeemolekyuli C28H29NO5
IMisa yeMolar 459.53
Ukuxinana 1.218±0.06 g/cm3(Kuxelwe kwangaphambili)
Indawo yokunyibilika ~150°C (ngoDisemba)
Indawo yeBoling 658.2±55.0 °C(Kuqikelelwe)
Ujikelezo oluthile(α) -28 º (c=1, DMF)
Indawo yokuflasha 351.9°C
Ukunyibilika I-Chloroform (Kancinci), i-DMF (Kancinci), i-Methanol (Kancinci)
Uxinzelelo loMphunga 3.2E-18mmHg ku-25°C
Imbonakalo Ikristale emhlophe
Umbala Mhlophe
I-BRN 4216652
pKa 2.97±0.10(Kuqikelelwe)
Imeko yoGcino Gcina ngaphantsi +30°C.
Refractive Index -30 ° (C=1, DMF)
MDL MFCD00037129
IiPropati zoMzimba kunye nezeMichiza Umgubo omhlophe wekristale; Ayinyibiliki emanzini nakwi-petroleum ether, enyibilikayo kwi-ethyl acetate, i-methanol kunye ne-DMF;mp yi-150-151 ℃; Ukujikeleza okuthe ngqo kokubona [α]20D 10 5.2 °(0.5-2.0 mg/ml, ethyl acetate),[α]20D-27.6 °(0.5-2.0 mg/ml,DMF),[α]20D-6 °(0.5- 2.0 mg / ml, methanol).

Iinkcukacha zeMveliso

Iithegi zeMveliso

Iimpawu ezinobungozi Xi – Irritant
Iikhowudi zoMngcipheko 36/37/38 – Ukucaphukisa amehlo, inkqubo yokuphefumula kunye nolusu.
Inkcazelo yoKhuseleko S26 – Xa udibana namehlo, hlambulula ngokukhawuleza ngamanzi amaninzi kwaye ufune iingcebiso zonyango.
S24/25-Kuphephe ukudibana nolusu namehlo.
WGK eJamani 3
Ikhowudi ye-HS 2924 29 70

 

Intshayelelo

I-Fluorene methoxycarbonyl-oxotert-butyl-tyrosine yikhompawundi yemichiza ehlala ifinyezwa njenge-FMOC-Tyr(tBu)-OH. Oku kulandelayo sintshayelelo kubume bayo, ukusetyenziswa, ukulungiswa kunye nolwazi lokhuseleko:

 

Umgangatho:

- Imbonakalo: Emhlophe okanye emhlophe eqinileyo.

- Ukunyibilika: Inyibilika kwezinye izinyibilikisi ze-organic, njenge-dimethyl sulfoxide kunye ne-dimethylformamide.

 

Sebenzisa:

- Ukukhusela amaqela kwi-chemical synthesis: Amaqela e-FOC angasetyenziselwa ukukhusela amaqela e-amino kwi-phenolic compounds ukukhusela ukuba bangaphenduli. I-FMOC-Tyr (tBu) -OH ingasetyenziselwa njengento yokuqala yokulungiswa kwamaketanga e-peptide kwi-chemical synthesis.

 

Indlela:

Indlela yokulungiselela ye-FOC-Tyr(tBu)-OH inokufezekiswa ngala manyathelo alandelayo:

- I-Fluorenyl chloride (FMOC-Cl) ithathwa kunye ne-tert-butyl (tBu-NH2) ukunika i-fluorenylmethoxycarbonyl-tert-butichsyl (FMOC-tBu-NH-).

- Emva koko, phendula isiphumo se-FOC-tBu-NH- kunye ne-tyrosine (Tyr-OH) ukuvelisa i-FMOC-Tyr (tBu)-OH.

 

Ulwazi ngoKhuseleko:

- Ukusetyenziswa kwe-FMOC-Tyr (tBu)-OH ixhomekeke ekuthotyelweni kwemigaqo yokhuseleko lwebhubhoratri.

• Kuphephe ukudibana nolusu kunye namehlo, kwaye unxibe iiglavu ezikhuselayo kunye neglasi xa usebenzisa.

- Sebenzisa kwindawo engena umoya, kude nomlilo kunye nezinto ezinokutsha.

- Makungakhutshelwa kwimo engqongileyo kwaye kufuneka iphathwe kwaye ilahlwe ngokuhambelana nemimiselo yendawo.

 

  • Ngaphambili:
  • Okulandelayo:
    • Bhala umyalezo wakho apha kwaye uwuthumele kuthi

    iimveliso ezinxulumene