Ftorafur (CAS#17902-23-7)
| Iimpawu ezinobungozi | T – Inetyhefu |
| Iikhowudi zoMngcipheko | 23/24/25 – Ityhefu ngokuphefumla, xa udibana nesikhumba kwaye xa uginyiwe. |
| Inkcazelo yoKhuseleko | S22 – Musa ukuphefumla uthuli. S36/37/39 – Nxiba iimpahla ezifanelekileyo zokukhusela, iiglavu kunye nokukhusela amehlo/ubuso. S45 - Kwimeko yengozi okanye ukuba uziva ungaphilanga, funa iingcebiso zonyango ngokukhawuleza (bonisa ileyibhile nanini na kunokwenzeka.) |
| Izazisi ze-UN | UN 2811 6.1/PG 2 |
| WGK eJamani | 3 |
| RTECS | YR0450000 |
| Ikhowudi ye-HS | 29349990 |
| IKlasi yeeNgozi | 6.1 |
| Iqela lokuPakisha | II |
| Ubutyhefu | I-LD50 kwiigundane (mg / kg): 900 ngomlomo (iintsuku ezi-3) (Yasumoto); I-750 ip (FR 1574684), nayo ichazwe njenge-1150 ip (Smart) |
Intshayelelo
I-Trifluoromethylation yi-organic chemical reaction apho amaqela e-trifluoromethyl anokwaziswa kwiimolekyuli eziphilayo zisebenzisa i-tegafluor reagents ezifana ne-TMSCF3.
Iimpawu zetegafluor:
- I-Tegafluor yinkqubo ebalulekileyo yokuguqulwa kweqela, enokwazisa amaqela e-trifluoromethyl kunye noxinaniso oluthile lwe-electron ukutshintsha iimpawu ezibonakalayo kunye neekhemikhali ze-molecule.
- Amaqela e-Trifluoromethyl anomdla oqinileyo we-electron, onokunyusa i-electrophilicity ye-molecule kunye ne-solubility ye-solvent.
- Iimveliso ze-tegafluor reaction zihlala zizinzile ngokwekhemikhali kwaye zisebenza ngokwebhayoloji.
Ukusetyenziswa kwe-tegafluor:
- Kwintsimi yezinto zesayensi, i-tegafluor inokutshintsha iipropati zomphezulu wezinto eziphathekayo, ukwandisa ukuzinza kunye nokuchasana kwemozulu.
Indlela yokulungiselela i-tegafluor:
- I-reagents ye-tegafluor esetyenziswa ngokuqhelekileyo iquka: TMSCF3, i-Ruppert-Prakash reagent, njl.
- Iimpendulo ze-Tegafluor zidla ngokuqhutyelwa kwi-atmosphere ye-inert, kusetyenziswa i-solvent ye-inert (umzekelo, i-methylene chloride, i-chloroform) njengendlela yokusabela.
- Iimeko zokusabela zifuna ubushushu obuphezulu bokusabela kunye namaxesha okusabela amade, kwaye zihlala zifuna ukongezwa kwe-catalyst (umz., i-copper catalyst).
Ulwazi ngokhuseleko kwi-tegafur:
- Iirejenti zeTegafluor ziyityhefu kwaye ziyadla, kwaye amanyathelo okhuseleko afanelekileyo kufuneka athathwe xa uphathwa.
- Iigesi (umz. i-hydrogen fluoride) eziveliswayo ngexesha lokusabela nazo ziyingozi kwaye kufuneka ziqhutywe phantsi kweemeko ezinomoya owaneleyo.
- Ukunyamekela kufuneka kuthathwe ukuphepha ukudibana namanzi okanye ukufuma ngexesha lokusebenza ukuphepha ukuphendula kweekhemikhali ezingenakuguqulwa.
- I-reactants kunye neemveliso phantsi kweemeko zokusabela kwe-tegafluor zifuna unyango olufanelekileyo kunye nokulahlwa kwenkunkuma.
