L-3-Aminoisobutyric acid (CAS# 4249-19-8)

Intshayelelo

I-Sb-aminoisobutyric acid (S-β-aminoisobutyric acid) i-amino acid enesakhiwo esithile. I-amino acid engekho ngokwemvelo kunye ne-molecular formula ye-C4H9NO2 kunye ne-molecular weight ye-103.12g / mol.

I-Sb-aminoisobutyric acid yenye ye-stereoisomers ezimbini, kwaye ukucwangciswa kwayo kwe-stereo kuhlala kwifom ye-L. Ingumgubo omhlophe wekristale, onyibilikayo emanzini kunye nezinyibilikisi zotywala. Ikhompawundi izinzile emoyeni kodwa ivakalelwa kubushushu kunye nokukhanya.

I-Sb-aminoisobutyric acid inemisebenzi emininzi ebalulekileyo ye-physiological in vivo, kuquka iprotheni ye-metabolism, ukulawulwa kwe-immune kunye nefuthe ekusebenzeni kwengqondo. Isenokusetyenziswa njenge-chiral ehlawuliswayo kunye ne-fatty acid oxidase carrier intracellular carrier.

I-asidi ye-Sb-aminoisobutyric isetyenziswa kakhulu kwintsimi yeyeza lamachiza okwenziwa, unyango oluchasene nomhlaza kunye nophando lwe-biochemical. Ingasetyenziselwa ukufunda umsebenzi weeprotheni kunye ne-enzymes, ukwakheka kweeprotheni kunye ne-nucleic acids, kunye nokudibanisa i-antibiotics, i-analgesics kunye nezinye iikhompawundi ze-bioactive.

Iindlela zokulungiselela i-Sb-aminoisobutyric acid inokwenziwa okanye ikhutshwe kwimithombo yendalo. Enye indlela eqhelekileyo yokwenziwa kukuxutywa kwe-isovaleraldehyde. Ukukhutshwa kwimithombo yendalo ngokuqhelekileyo kuvela kwi-metabolites yeebhaktheriya ezithile okanye i-fungi.

Ngokumalunga nolwazi lokhuseleko, i-Sb-aminoisobutyric acid ngokuqhelekileyo ithathwa njengekhuselekile xa kusetyenziswe ushishino ngokubanzi kunye nemisebenzi yaselabhoratri. Nangona kunjalo, iseyikhemikhali kwaye kufuneka ixhomekeke kwiinkqubo ezifanelekileyo zokhuseleko lwaselabhoratri. Xa ebhengezwe kuyo, kufuneka athathe amanyathelo okhuseleko afanelekileyo, kuquka ukunxiba iiglavu, iiglasi kunye nempahla yokuzikhusela. Kwimeko yokudibana ngengozi okanye ukungeniswa, unyango kufuneka lufunwe ngokukhawuleza.