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Levodopa (CAS# 59-92-7) Umfanekiso okhoyo
  • Levodopa(CAS# 59-92-7) 1

Levodopa (CAS# 59-92-7)

Ipropati yeMichiza:

Ifomula yeemolekyuli C9H11NO4
IMisa yeMolar 197.19
Ukuxinana 1.3075 (uqikelelo olurhabaxa)
Indawo yokunyibilika 276-278 °C (isibane.)
Indawo yeBoling 334.28°C (uqikelelo olurhabaxa)
Ujikelezo oluthile(α) -11.7 º (c=5.3, 1N HCl)
Indawo yokuflasha 225°C
Ukunyibilika kwamanzi I-soluble kancinane emanzini, i-dilute i-hydrochloric acid kunye ne-fomic acid. Ayinyibiliki kwi-ethanol.
Ukunyibilika Inyibilika ngokulula kwi-dilute hydrochloric acid kunye ne-formic acid, inyibilika emanzini, ayinyibiliki kwi-ethanol, ibenzene, ichloroform kunye ne-ethyl acetate.
Uxinzelelo loMphunga 7.97E-09mmHg ku-25°C
Imbonakalo Umgubo wekristale omhlophe ukuya kumhlophe
Umbala Imhlophe ukuya kukhrim
Merck 14,5464
I-BRN 2215169
pKa 2.32(nge-25℃)
Imeko yoGcino 2-8°C
Uzinzo Izinzile. Ayihambelani ne-oxidizing agents ezinamandla. Ukukhanya kunye nomoya obuthathaka.
Inovakalelo Uvakalelo kukukhanya kunye nomoya
Refractive Index -12 ° (C=5, 1mol/LH
MDL MFCD00002598
IiPropati zoMzimba kunye nezeMichiza indawo yokunyibilika ngama-295°C
ukujikeleza okucacileyo kwe-optical -11.7 ° (c = 5.3, 1N HCl)
Sebenzisa Ichiza elisebenzayo lokunyanga ukukhubazeka kokuphazamiseka, ikakhulu esetyenziselwa i-Parkinson's syndrome, njl

Iinkcukacha zeMveliso

Iithegi zeMveliso

Iimpawu ezinobungozi Xn – Iyingozi
Iikhowudi zoMngcipheko I-R22 – Iyingozi xa iginyiwe
R36/37/38 – Ukucaphuka kwamehlo, inkqubo yokuphefumla kunye nolusu.
I-R20/21/22 – Iyingozi ngokuphefumla, xa udibana nolusu naxa uginyiwe.
Inkcazelo yoKhuseleko S26 – Xa udibana namehlo, hlambulula ngokukhawuleza ngamanzi amaninzi kwaye ufune iingcebiso zonyango.
S36 – Nxiba iimpahla ezifanelekileyo ezikhuselayo.
S24/25-Kuphephe ukudibana nolusu namehlo.
WGK eJamani 3
RTECS AY5600000
FLUKA BRAND F IIKHOWUDI 10-23
I-TSCA Ewe
Ikhowudi ye-HS 29225090
Ubutyhefu I-LD50 kwiigundane (mg / kg): 3650 ±327 ngomlomo, 1140 ± 66 ip, 450 ± 42 iv,> 400 sc; kwinkunzi, iimpuku zasemazi (mg/kg):>3000,>3000 ngomlomo; 624, 663 ip; >1500, >1500 sc (Clark)

 

Intshayelelo

Iziphumo ze-Pharmacological: anti-tremor paralysis drug. Ingena kwizicubu zobuchopho ngesithintelo segazi-ingqondo, kwaye i-decarboxylated yi-dopa decarboxylase kwaye iguqulwa ibe yi-dopamine, edlala indima. Isetyenziselwa ukungcangcazela ukukhubazeka okuphambili kunye ne-non-drug-induced tremor paralysis syndrome. Unefuthe elihle kubantu abadala abaphakathi nabathobekileyo, abaqatha okanye abahluphekayo.

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