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Metadoxine(CAS# 74536-44-0) Umfanekiso okhoyo
  • Metadoxine(CAS# 74536-44-0) 1

Metadoxine (CAS# 74536-44-0)

Ipropati yeMichiza:

Ifomula yeemolekyuli C8H11NO3.C5H7NO3
IMisa yeMolar 298.293
Indawo yokunyibilika 102-104°C
Ukunyibilika I-DMSO (Kancinci), iMethanol (Kancinci)
Imbonakalo Iqinile
Umbala Mhlophe ukuya kuMthubi oKhanyayo
Imeko yoGcino Itywinwe kwindawo eyomileyo,2-8°C
Sebenzisa Ukumiselwa komxholo yi-HPLC
Isifundo se-in vitro Unyango lwe-Metadoxine ngaxeshanye lunqanda ulwahlulo lwe-adipogenic ngendlela exhomekeke kwithamo. Unyango lwe-metadoxine ukusuka kusuku lwesi-4 ukuya kusuku lwesi-8 luyafuneka ukuze kuthintelwe ulwahlulo lwe-preadipocyte olubangelwa yi-MDI. I-Metadoxine ikhusela ukuchithwa kwe-glutathione kunye nokunyuka komonakalo we-lipid peroxidation obangelwa yi-ethanol kunye ne-acetaldehyde kwiiseli ze-HepG2. Kwiiseli ze-hepatic stellate, i-Metadoxine inqanda ukwanda kwe-collagen kunye ne-attenuated TNF-α secretion ebangelwa yi-acetaldehyde. Ke, iMetadoxine inokuba luncedo ekuthinteleni umonakalo oveliswe kumanqanaba okuqala esifo sesibindi esinxilisayo njengoko ithintela ukungalingani kwe-redox ye-hepatocytes kwaye ithintele ukufakwa kwe-TNF-α, esinye seziganeko zokuqala kumonakalo wesibindi.

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Intshayelelo

I-Metadoxin, ngokwekhemikhali eyaziwa ngokuba yi-N,N-dimethylformamide, lulwelo olungenambala. Iimpawu zayo zezi zilandelayo:

 

Iimpawu ezibonakalayo: I-Metadoxine lulwelo olungenambala olunevumba elinukayo, oluguquguqukayo kubushushu begumbi, luxubene namanzi kunye nezona zinyibiliki zixhaphakileyo.

 

Iimpawu zeMichiza: I-Metadoxine yikhompawundi enciphisa kakhulu enokuthi ifakwe i-hydrolyzed nge-sodium hydroxide okanye izisombululo ze-sodium carbonate ukwenza i-formamide kunye ne-methanol.

 

Ukusetyenziswa kwe-metaxacin:

 

I-Catalyst: I-Metadoxine inokusetyenziselwa ukuthwala i-catalysts yesinyithi, kwaye isetyenziselwa ukwenza i-formylation reaction ye-amines kwi-organic synthesis.

 

Izinyibilikisi: I-Metadoxine isetyenziswa kakhulu njengesinyibilikisi kwi-organic synthesis, njengokunyibilikisa izakhiwo zetsimbi, iipolymers, kunye neziphakathi ukwenzela ukusabela kwe-catalytic.

 

Indlela yokulungiselela: Ukulungiswa kwe-metadoxine ngokuqhelekileyo kufunyanwa ngokusabela kwe-formamidine kunye ne-asidi ye-formic.

 

Ulwazi ngokhuseleko: I-Metaxacin iyacaphuka kwaye iyadla, kwaye inefuthe elicaphukisayo eluswini, emehlweni kunye nakwimifinya. Kufuneka kuqwalaselwe ukuthintela ukudibana ngqo nolusu kunye namehlo, kwaye iiglavu ezikhuselayo kunye nezibuko kufuneka zinxitywe ukuba kuyimfuneko. Ingqalelo kufuneka ihlawulwe ekungeneni komoya ngexesha lokusetyenziswa ukuphepha ukuphefumla umphunga wayo. I-Meltadoxine yinto enokutsha kwaye kufuneka igcinwe kude namadangatye avulekileyo kunye nemithombo yobushushu obuphezulu.

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