IMethoxymethyl triphenylphosphonium chloride (CAS# 4009-98-7)

Usebenzisa

(iMethoxymethyl) i-triphenylphosphorus chloride isetyenziselwa ukwenza i-cefaltacin, ichiza le-antiviral kunye ne-anti-tumor. Ikwasetyenziselwa ukwenza iqhekeza le-paclitaxel.

Ukulungiselela

Indlela yokudibanisa (i-methoxymethyl) i-triphenylphosphorus chloride, equka la manyathelo alandelayo: phantsi kokhuseleko lwe-nitrogen, yongeza i-50mL ye-acetone ye-anhydrous kwi-reactor, emva koko yongeza i-32g ye-triphenylphosphine, ivuselela kwaye iphakamise ubushushu ukuya kwi-37 ° C, igcina iqondo lokushisa rhoqo. , yongeza i-20g ye-methyl chloromethyl ether kwi-reactor, kwaye emva koko iphendule I-37 ° C ye-3h, iphakamisa ngokukhawuleza iqondo lokushisa ukuya kwi-47 ° C kwizinga le-1 ° C / min, ukuphendulwa kwaqhubeka kwi-3h, ukuphendula kwamiswa, kunye ne-37.0g (methoxymethyl) i-triphenylphosphorus chloride yafunyanwa ngokucoca, i-anhydric. ukuhlamba i-ether kunye nokomisa ngesivuno se-88.5%.