I-N-Carbobenzyloxy-L-proline(CAS# 1148-11-4)
I-Cbz-L-Proline, egama layo elipheleleyo ngu-L-Proline-9-Butyroyl Ester, i-organic compound. Oku kulandelayo sintshayelelo kwiipropati, ukusetyenziswa, iindlela zokulungiselela kunye nolwazi lokhuseleko lwe-Cbz-L-proline:
Umgangatho:
- Imbonakalo: Ikristale emhlophe okanye i-crystalline powder.
- Ukunyibilika kwetyuwa: ukunyibilika kwiiasidi, akunyibiliki emanzini.
Sebenzisa:
- I-Cbz-L-proline isoloko isetyenziswa njengeqela elikhuselayo kwi-organic synthesis ukukhusela amaqela e-amino (NH₂) kwii-amino acids.
- Isetyenziswa ikakhulu kwi-chemical synthesis ye-peptides kunye neeprotheni.
Indlela:
Ukulungiswa kwe-Cbz-L-proline ngokubanzi kwenziwa ngala manyathelo alandelayo:
1. I-Proline iphendulwa nge-chloroformate-9-butyl ester phantsi kweemeko ze-alkaline ukufumana i-substrate.
2. I-Substrate iphathwa phantsi kweemeko ze-acidic ukuvelisa i-Cbz-L-proline.
Ulwazi ngoKhuseleko:
- I-Cbz-L-Proline yikhemikhali kwaye kufuneka iphathwe ngononophelo. Qaphela ukuba uthintele ulusu kunye namehlo, kwaye uphephe ukuphefumla.
-Nxiba izixhobo ezifanelekileyo zokuzikhusela ezifana neeglavu zaselebhu kunye neglavu xa usetyenziswa.
- Gcina ivalwe ngokuqinileyo kwaye ugweme ukukhanya kwelanga kunye namaqondo obushushu aphezulu.
- Emva kokusetyenziswa kunye nokuphathwa, landela imigaqo yendawo yokulahla imichiza.
