N-BOC-L-Arginine hydrochloride (CAS# 35897-34-8)
| Inkcazelo yoKhuseleko | S22 – Musa ukuphefumla uthuli. S24/25-Kuphephe ukudibana nolusu namehlo. |
| WGK eJamani | 3 |
| Ikhowudi ye-HS | 29252900 |
| IKlasi yeeNgozi | OKUTHUMEKAYO |
Intshayelelo
I-Boc-L-Arg-OH.HCl(Boc-L-Arg-OH.HCl) yikhompawundi ephilayo enezi mpawu zilandelayo:
1. ukubonakala: umgubo omhlophe oqinileyo.
2. I-Solubility: I-Soluble emanzini kunye ne-solvents ye-organic efana ne-methanol, i-ethanol, njl.
3. Ukuzinza: Iyazinza kwiqondo lobushushu begumbi, kodwa kulula ukufunxa ukufuma xa ibekwe kubumanzi okanye kubumanzi.
I-Boc-L-Arg-OH.HCl inokusetyenziswa kulandelayo kuphando lwekhemikhali kunye nokuhlanganiswa:
1. Uphando lomsebenzi webhayoloji: njenge-synthetic intermediate ye-peptide kunye neprotheni, isetyenziselwa ukwakha ikhonkco le-peptide.
2. uphando ngamachiza: ukwenzela ukuhlanganiswa kweziyobisi ze-peptide ze-bioactive kunye ne-antibiotics.
3. Uhlalutyo lweekhemikhali: lusetyenziswe njengomgangatho wohlalutyo lwe-mass spectrometry.
Indlela yokulungiselela i-Boc-L-Arg-OH.HCl ikakhulu ibandakanya la manyathelo alandelayo:
1. i-tert-Butyloxycarbonylation: I-L-arginine isabela nge-tert-butyloxycarbonyl chloride (Boc-Cl) phantsi kweemeko ze-alkaline ukufumana i-tert-butoxycarbonyl-L-arginine.
2. Ukubunjwa kwetyuwa ye-Hydrochloride: i-tert-Butoxycarbonyl-L-arginine yaphendulwa nge-hydrochloric acid ukufumana i-Boc-L-Arg-OH.HCl.
Ngokumalunga nolwazi lokhuseleko, i-Boc-L-Arg-OH.HCl ikhuselekile ngokwentelekiso phantsi kweemeko zokusetyenziswa kwesiqhelo, le miba ilandelayo kusafuneka inikwe ingqwalasela:
1. Kuphephe ukuphefumla uthuli okanye ukudibana kwesikhumba: Nxiba iiglavu ezikhuselayo, iiglasi kunye nemaski ukuphepha ukunxibelelana ngokuthe ngqo okanye ukuphefumla uthuli.
2. izilumkiso zokugcina: kufuneka zigcinwe kwindawo eyomileyo, epholileyo, indawo engenamoya, ukuphepha ukukhanya kwelanga.
3. Ukulahlwa kwenkunkuma: Inkunkuma kufuneka ilahlwe ngokufanelekileyo ngokuhambelana nemigaqo yendawo kwaye ingalahlwa ngeenkqubo zokucocwa kwenkunkuma yeekhemikhali.
