I-N-Boc-N'-trityl-L-glutamine (CAS# 132388-69-3)
Umngcipheko kunye noKhuseleko
| WGK eJamani | 3 |
| Ikhowudi ye-HS | 29242990 |
Intshayelelo
2. ifomula yemolekyuli: C39H35N3O6
3. Ubunzima bemolekyuli: 641.71g / mol
4. Indawo yokunyibilika: 148-151°C
5. I-Solubility: I-Soluble kwi-solvents ezininzi zezinto eziphilayo, ezifana ne-dimethyl sulfoxide (DMSO) kunye ne-dichloromethane.
6. Uzinzo: uzinzile phantsi kweemeko eziqhelekileyo zovavanyo.
Kwi-chemical synthesis, i-N-Boc-N '-trityl-L-glutamine isoloko isetyenziswa njengeqela elikhuselayo le-amino acid okanye eliphakathi. Usetyenziso lwayo oluphambili lubandakanya:
1. isetyenziswe njengeqela lokukhusela i-glutamine kwi-peptide kunye neprotheni synthesis.
2. Kuphando lweziyobisi zokwenziwa, isetyenziselwa ukudibanisa i-glutamine analogs.
3. isetyenziswe njengendawo ephakathi ukudibanisa ezinye iikhompawundi eziphilayo.
Indlela yokulungiselela i-N-Boc-N '-trityl-L-glutamine ngokubanzi ngolu hlobo lulandelayo:
1. Okokuqala, phendula i-N-protected glutamine (njenge-N-Boc-L-glutamine) kunye ne-trityl halide (njenge-trityl chloride) ukufumana i-N-Boc-N '-trityl-L-glutamine.
Ulwazi ngoKhuseleko:
I-N-Boc-N '-trityl-L-glutamine, njengekhompawundi ephilayo, ikhuselekile xa iphantsi kokusetyenziswa ngokuchanekileyo kunye nokugcinwa. Nangona kunjalo, le miba ilandelayo isafuna ukuqatshelwa:
1. Kuphephe ukudibana namehlo, ulusu kunye nomgudu wokuphefumula. Sebenzisa iiglavu zokukhusela iikhemikhali kunye nezibuko.
2. Gcina kwindawo eyomileyo, epholileyo.
3. Ukuthobela iinkqubo zokhuseleko kwaye uphathe ngokufanelekileyo kwaye ulahle inkunkuma yekhompawundi.
