N-Cbz-D-Serine(CAS# 6081-61-4)
| Inkcazelo yoKhuseleko | S22 – Musa ukuphefumla uthuli. S24/25-Kuphephe ukudibana nolusu namehlo. |
Intshayelelo
I-N-Benzyloxycarbonyl-D-serine(N-Benzyloxycarbonyl-D-serine) yikhompawundi ephilayo. Inezi mpawu zilandelayo:
Imbonakalo: Ngokuqhelekileyo i-crystalline powder engenambala okanye emhlophe.
Ifomula yemolekyuli: C14H15NO5
Ubunzima bemolekyuli: 285.28g/mol
Ukunyibilika: Inyibilika kwezinye izinyibilikisi eziphilayo, ezifana neklorofomu kunye nemethanol.
I-N-Benzyloxycarbonyl-D-serine isoloko isetyenziswa njengeziphakathi kwi-synthesis kunye nokufundwa kwezinye iikhompawundi. Yinto ebalulekileyo kwintsimi yekhemistri yamachiza kunye nezinto eziphathekayo kwaye inoluhlu olubanzi lwezicelo.
Indlela eqhelekileyo yokulungiselela i-N-Benzyloxycarbonyl-D-serine kukuphendula i-D-serine nge-N-benzyloxycarbonylchloromethane. Okokuqala, i-D-serine yachithwa kwisisombululo se-sodium bicarbonate, kwaye i-N-benzyloxycarbonylchloromethane yongezwa. Emva kokuba i-reaction yenziwe, imveliso inokuhlanjululwa ngakumbi ngokungathathi hlangothi kunye nesisombululo se-acidic kunye ne-extract extraction kunye ne-crystallization.
Ngokumalunga nolwazi lokhuseleko, ubutyhefu be-N-Benzyloxycarbonyl-D-serine buphantsi, kodwa le miba ilandelayo isafuna ukuqatshelwa:
-Le yikhemikhali kwaye kufuneka ithathelwe ingqalelo ukuphepha ukudibanisa nesikhumba, umlomo kunye namehlo. Nxiba amanyathelo afanelekileyo okukhusela, afana neeglavu, iiglasi zokhuseleko kunye neengubo zaselabhoratri.
-Xa uphatha okanye usebenzisa, kufuneka kwenziwe kwindawo epholileyo ukuze ugweme ukuphefumla okanye ukugwinya into.
-Ngexesha lokugcinwa kunye nokuphatha, imisebenzi echanekileyo yokhuseleko lwebhubhoratri kufuneka ilandelwe.
Ngaphambi kokusebenzisa i-N-Benzyloxycarbonyl-D-serine, kuyacetyiswa ukuba ufunde uxwebhu olufanelekileyo lwedatha yokhuseleko kunye nemiyalelo yokhuseleko lwezinto eziphathekayo ngokweenkcukacha ukuqinisekisa ukusebenza ngokukhuselekileyo.
