Iindlela ezivelayo kwimarike ye-3,5-di-tert-butyl-4-hydroxybenzaldehyde: abaphakathi kwezamayeza e-United States naseYurophu.

Imfuno yoshishino lwamayeza kumaziko aphakathi akumgangatho ophezulu, ayimfuneko ekudibaneni kweekhompawundi ezahlukeneyo zonyango, ikhule kakhulu kwiminyaka yakutshanje. Phakathi kwezi ziphakathi, i-3,5-di-tert-butyl-4-hydroxybenzaldehyde (CAS#1620-98-0) uye waba ngumdlali ophambili kwiimarike zaseMelika naseYurophu. Eyaziwayo ngeempawu zayo ezikhethekileyo zeekhemikhali kunye nokuguquguquka, le khompawundi isetyenziswa ngakumbi ekuveliseni amayeza, i-agrochemicals kunye neekhemikhali ezikhethekileyo.

I-3,5-di-tert-butyl-4-hydroxybenzaldehyde yamkelwa ngokuyintloko ngendima yayo njengendawo yokuthengisa amayeza. Yizinto ezisisiseko zokwenziwa kwezinto ezahlukeneyo ezisebenzayo zamachiza (APIs), ngakumbi ezo zisetyenziselwa ukunyanga izifo ezingapheliyo ezifana nomhlaza, isifo senhliziyo, kunye nesifo se-metabolic syndrome. Isakhono sekhompawundi sokuphucula ukusebenza kunye nozinzo lwemixube yoxubo lwenze ukuba ibe sisithako esifunwayo kubenzi bamachiza.

I-US 3,5-di-tert-butyl-4-hydroxybenzaldehyde imakethi ifumana ukukhula olomeleleyo, okuqhutywa kukunyusa utyalo-mali kuphando nophuhliso (R&D) imisebenzi yeenkampani zamayeza. Ukunyuka kwezifo ezinganyangekiyo kunye nemfuno elandelayo yonyango olutsha kuye kwaqhubela phambili imfuno yabaphakathi abakumgangatho ophezulu. Ukongeza, ishishini lamayeza eliqolileyo kunye nemeko efanelekileyo yolawulo e-United States ibe negalelo ekukhuleni kokuthandwa kwale khompawundi.

EYurophu, imeko iyafana, kunye namazwe afana neJamani, iFransi kunye ne-UK ekhokela ukusetyenziswa kwe-3,5-di-tert-butyl-4-hydroxybenzaldehyde. Imarike yaseYurophu yamayeza iphawulwa ngemigangatho engqongqo kunye nemigaqo yomgangatho, ekhuthaza abavelisi ukuba bafune imithombo ethembekileyo yabaphakathi bamayeza. Ikhompawundi ihambelana nezikhokelo ze-European Medicines Agency (EMA), iyenza ibe lukhetho olunomtsalane kwiinkampani ezijonge ukomeleza iipotfoliyo zemveliso yazo.

Ukongeza, ukugxila okukhulayo kuzinzo kunye nezenzo zekhemistri eluhlaza e-United States naseYurophu kukhokelele ekutshintsheni kwimichiza ephakathi. Abavelisi ngoku babeka phambili ababoneleli ababambelela kwizenzo zokusingqongileyo, nto leyo eyandisa ngakumbi imfuno ye-3,5-di-tert-butyl-4-hydroxybenzaldehyde. Iinkampani ezinokubonisa ukuzinikela kwiindlela zemveliso ezinzileyo zinokufumana inzuzo yokhuphiswano kwimarike.

Ikhonkco lokubonelela nge-3,5-di-tert-butyl-4-hydroxybenzaldehyde nalo liyavela, kwaye abavelisi baphonononga amaqhinga amatsha okukhangela ukuqinisekisa ukubonelela okuzinzile kwesi siphakathi esibalulekileyo. Intsebenziswano phakathi kwabavelisi beekhemikhali kunye neenkampani ezixuba amayeza ziya zixhaphaka ngakumbi njengoko zombini zifuna ukwandisa iinkqubo zemveliso kunye nokunciphisa iindleko. Lo mkhwa kulindeleke ukuba uqhubeke njengoko imfuno yabaphakathi abakumgangatho ophezulu ihlala yomelele.

Ukuqukumbela, imakethi ye-3,5-di-tert-butyl-4-hydroxybenzaldehyde njengendawo ephakathi kwezamayeza kulindeleke ukuba ikhule kakhulu e-United States naseYurophu. Ukuguquguquka kwekhompawundi, ukuthobela imigangatho yolawulo kunye nokulungelelaniswa neenjongo zophuhliso oluzinzileyo kuyenza ibe yi-asethi enexabiso kushishino loxubo-mayeza. Njengoko imfuno yonyango olutsha iqhubeleka nokunyuka, ukubaluleka kweziphakathi ezithembekileyo nezikumgangatho ophezulu ezifana ne-3,5-di-tert-butyl-4-hydroxybenzaldehyde ziya kunyuka kuphela, zibumba ubume bexesha elizayo bokwenziwa kwamayeza kule mimandla.