Papaverine Hydrochloride(CAS#61-25-6)
| Iikhowudi zoMngcipheko | I-R22 – Iyingozi xa iginyiwe I-R34 – Ibangela ukutsha I-R11 – Iyatsha kakhulu |
| Inkcazelo yoKhuseleko | S22 – Musa ukuphefumla uthuli. S45 - Kwimeko yengozi okanye ukuba uziva ungaphilanga, funa iingcebiso zonyango ngokukhawuleza (bonisa ileyibhile nanini na kunokwenzeka.) S36/37/39 – Nxiba iimpahla ezikhuselayo ezifanelekileyo, iiglavu kunye nokhuseleko lwamehlo/ubuso. S26 – Xa udibana namehlo, hlambulula ngokukhawuleza ngamanzi amaninzi kwaye ufune iingcebiso zonyango. S16 – Gcina kude kwimithombo yomlilo. |
| Izazisi ze-UN | UN 1544 6.1/PG 3 |
| WGK eJamani | 1 |
| RTECS | NW8575000 |
| FLUKA BRAND F IIKHOWUDI | 8 |
| I-TSCA | Ewe |
| Ikhowudi ye-HS | 29391900 |
| IKlasi yeeNgozi | 6.1 |
| Iqela lokuPakisha | III |
| Ubutyhefu | I-LD50 kwiigundane, iigundane (mg / kg): 27.5, 20 iv; 150, 370 sc (Levis) |
Papaverine Hydrochloride(CAS#61-25-6)
I-Papaverine hydrochloride, inombolo ye-CAS 61-25-6, i-compound ebalulekileyo kwintsimi yamachiza.
Ukusuka kwindawo yokujonga iipropati zeekhemikhali, yifom ye-hydrochloride yepapaverine, kwaye isakhiwo samakhemikhali sinquma iimpawu zayo. Ukulungelelaniswa kwee-athomu kunye nokulungelelaniswa kwee-chemical bonds kwi-molecular structure inika uzinzo olulodwa kunye nokusebenza kwakhona. Inkangeleko ngokuqhelekileyo imhlophe ukuya kumgubo wekristale okhanyayo otyheli, olungele ukusetyenzwa, ukugcinwa kunye nokuthuthwa kwamachiza. Ngokubhekiselele kwi-solubility, ine-solubility ephakathi emanzini, kunye neendawo ezahlukeneyo ze-acid-base kunye neemeko zobushushu ziya kuchaphazela iimpawu zayo zokunyibilika, eyona nto ibalulekileyo ekuqulunqweni kwamachiza, ukuphuhliswa kweefom zedosi, kunye nendlela yokuqinisekisa ukufana. ukusasazwa kweziyobisi xa kusenziwa iinaliti kunye namalungiselelo omlomo.
Ngokubhekiselele kwi-pharmacological efficacy, i-Papaverine Hydrochloride iyingxenye yeklasi ye-relaxants ye-muscle. Isebenza kakhulu kwi-muscle egudileyo yemithambo yegazi, i-gastrointestinal tract, i-biliary tract kunye nezinye iindawo, kwaye ikhuthaza ukukhululeka kwemisipha epholileyo ngokuphazamisa iindlela ezifana ne-intracellular calcium ion transport. Ngokonyango, isoloko isetyenziselwa ukunyanga i-ischemia ebangelwa yi-vasospasm, njengentloko kunye nesiyezi esibangelwa yi-vasospasm ye-cerebral, enokuphucula ukujikeleza kwegazi lendawo; Kwakhona kunempembelelo ebalulekileyo yokunciphisa intlungu yesisu kunye ne-biliary colic ebangelwa yi-spasm yesisu, ukunciphisa intlungu yezigulane.
Nangona kunjalo, njengakumachiza amaninzi, kubalulekile ukulandela imiyalelo kagqirha wakho xa uwasebenzisa. Ngenxa yemisebenzi eyahlukeneyo yomzimba kunye nezifo ezisisiseko zezigulane ngamnye, oogqirha kufuneka balinganise iminyaka yesigulane, isibindi kunye nokusebenza kwezintso, ezinye iziyobisi ezithathwayo kunye nezinye izinto, kwaye zichaze ngokuchanekileyo umthamo, indlela yokulawula kunye nekhosi yeyeza, ukuqinisekisa ukuba iyeza likhuselekile kwaye liyasebenza, kwaye lincede isigulana sichache. Ngenkqubela-phambili yophando lwenzululwazi, uphando kunye nophuhliso lweefomu zedosi entsha kunye nokwandisa amayeza adibeneyo ajikelezayo nawo ayafudumala.
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