iphepha_ibhena

imveliso

S-4-Chloro-alpha-methylbenzyl utywala CAS 99528-42-4

Ipropati yeMichiza:

Ifomula yeemolekyuli C8H9ClO
IMisa yeMolar 156.61
Ukuxinana 1.175 g/mL kwi-25 °C
Indawo yeBoling 240.6±15.0 °C(Kuqikelelwe)
Ujikelezo oluthile(α) -48 º (C=1 KWICHLOROFORM)
Indawo yokuflasha 110°C
pKa 14.22±0.20(Kuxelwe kwangaphambili)
Imeko yoGcino Itywinwe kwindawo eyomileyo, yoBubushushu beGumbi
Refractive Index n20/D 1.544
Sebenzisa Usetyenziso (S) -1-(4-chlorophenyl) i-ethanol yimathiriyeli ekrwada esisiseko yokudityaniswa kwenoveli N,N'-dimethylpiperazine enobuchule bokubopha isinyithi.

Iinkcukacha zeMveliso

Iithegi zeMveliso

Umngcipheko kunye noKhuseleko

Iimpawu ezinobungozi Xn – Iyingozi
Iikhowudi zoMngcipheko I-R20/21/22 – Iyingozi ngokuphefumla, xa udibana nolusu naxa uginyiwe.
R36/37/38 – Ukucaphuka kwamehlo, inkqubo yokuphefumla kunye nolusu.
Inkcazelo yoKhuseleko I-26 - Kwimeko yokunxibelelana namehlo, hlambulula ngokukhawuleza ngamanzi amaninzi kwaye ufune iingcebiso zonyango.
WGK eJamani 3

99528-42-4 - Indalo

ukujikeleza okuthe ngqo -48 ° (C=1 KWICHLOROFORM)
umsebenzi wamehlo (umsebenzi wokukhanya) [α]20/D -48.0 °, c = 1 kwiklorofomu

99528-42-4 - Iinkcukacha zeNgcaciso

sebenzisa (S) -1-(4-chlorophenyl) i-ethanol yimathiriyeli ekrwada esisiseko yokwenziwa kohlobo olutsha lwe-N,N'-dimethylpiperazine enobuchule bokubopha isinyithi.

 

Intshayelelo emfutshane
(S)-1-(4-chlorophenyl) ithanol yikhompawundi ephilayo. Yimolekyuli ye-chiral ene-chiral eyandisiweyo efana nesangqa. Oku kulandelayo sintshayelelo kwiipropati, ukusetyenziswa, iindlela zokulungiselela kunye nolwazi lokhuseleko lwale khompawundi:

Umgangatho:
- Imbonakalo: (S)-1-(4-chlorophenyl)thanol lulwelo olungenambala ukuya kumthubi okhanyayo.
-Inyibilika: Inokunyibilika kwizinyibilikisi ezininzi zezinto eziphilayo, ezinjengeealkoholi, ii-ethers kunye neehydrocarbons ezinuka kamnandi.

Sebenzisa:
- (S) -1-(4-chlorophenyl)thanol isetyenziswa ngokuqhelekileyo njengendawo ephakathi kwi-organic synthesis.
- Inokusetyenziswa kwakhona ekulungiseleleni i-chiral compounds, i-chiral ligands, kunye ne-chiral catalysts, phakathi kwabanye.

Indlela:
- (S)-1-(4-chlorophenyl)thanol inokudityaniswa ngala manyathelo alandelayo:
1. I-ethylene acetonitrile ixutywe nge-4-chlorobenzaldehyde ukwenza i-N-[(4-chlorobenzene)methyl]ethyleneacetonitrile.
2. Le intermediate ke ifudunyezwe sodium hydroxide kunye ethanol ukuvelisa (S) -1- (4-chlorophenyl) ethanol.

Ulwazi ngoKhuseleko:
- (S)-1-(4-chlorophenyl) ethanol ngokubanzi ikhuselekile ngokwentelekiso phantsi kweemeko eziqhelekileyo zokusebenza, kodwa kusekho iinkqubo ezithile zokusebenza ezisisiseko zokhuseleko lwaselabhoratri ekufuneka zilandelwe.
- Inokuba yinto ecaphukisayo yamehlo, ulusu, kunye nomgudu wokuphefumula kwaye kufuneka igwenywe ekudibaneni ngokuthe ngqo kunye nokuphefumla. Izixhobo ezifanelekileyo zokuzikhusela ezinjengeeglavu, iindondo zokuzikhusela, kunye nemaski kufuneka zinxitywe ngexesha lokuphatha.
- Xa uphatha okanye ugcina i-compound, kufuneka kuthathelwe ingqalelo ukuphepha ukutshisa kunye nokushisa okuphezulu.
- Xa usebenzisa kwaye ulahla, bhekisa kuKhuseleko lweeNkcukacha zeDatha kunye neeleyibhile zeekhemikhali, kwaye ulandele izikhokelo zokusebenza ukuqinisekisa ukhuseleko kunye nempilo yomngcipheko iyancitshiswa.


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