(S)-N-ALPHA-T-BUTYLOXYCARBONYL-PYROGLUTAMIC ACID T-BUTYL ESTER（CAS# 91229-91-3)
Intshayelelo
I-di-tert-butyl (2S) -5-oxopyrrolidine-1,2-dicarboxylate yi-compound ene-chemical formula yi-C14H23NO6. Oku kulandelayo yinkcazo yeepropati, ukusetyenziswa, ukulungiswa kunye nolwazi lokhuseleko lwekhompawundi:
Indalo:
-Ukubonakala: i-di-tert-butyl (2S) -5-oxopyrrolidine-1,2-dicarboxylate i-colorless crystalline solids.
-I-Solubility: Inyibilika kwii-solvents eziphilayo ezifana ne-ethanol, i-methanol kunye ne-dimethyl sulfoxide.
-Indawo yokunyibilika: Ikhompawundi iyanyibilika malunga ne-104-105°C.
Sebenzisa:
I-di-tert-butyl (2S) -5-oxopyrrolidine-1,2-dicarboxylate yinto esetyenziswa ngokuqhelekileyo i-amino acid derivative, edla ngokusetyenziswa njenge-reagent kwi-organic synthesis. Ingasetyenziselwa ukwenza iikhompawundi ezisebenzayo zebhayoloji, njengamachiza kunye nemathiriyeli yepolymer.
Indlela:
Ukulungiswa kwe-di-tert-butyl (2S)-5-oxopyrrolidine-1,2-dicarboxylate ngokuqhelekileyo kuqhutyelwa ngamanyathelo alandelayo:
1. Ukunyibilikisa i-pyroglutamic acid tert-butyl ester kwi-dimethyl sulfoxide eyomileyo.
2. Isixa esifanelekileyo se-N, N'-dihydroxyethyl isopropanamide songezwa kwaye umxube wokusabela wapholiswa ukuya ngaphantsi kwe-0 ° C.
3. Yongeza i-di-tert-butyl carbonate ngokucotha ngelixa ugcina ubushushu bomxube wokusabela ngaphantsi kwe-0°C.
4. Emva kokugqitywa kwempendulo, umxube wokuphendula wongezwa kumanzi ukuvelisa i-precipitate eqinile ye-di-tert-butyl (2S) -5-oxopyrrolidine-1,2-dicarboxylate.
5. Imveliso yokugqibela ifunyenwe ngamanyathelo e-crystallization, filtration kunye nokomisa.
Ulwazi ngoKhuseleko:
i-di-tert-butyl (2S) -5-oxopyrrolidine-1,2-dicarboxylate kufuneka isetyenziswe kwaye iphathwe ngokuhambelana nezenzo ezikhuselekileyo zokuphepha ukuvezwa kwesikhumba, amehlo kunye nokuphefumla. Ukongeza, kufuneka igcinwe kwindawo eyomileyo, epholileyo kwaye kude nomlilo kunye ne-oxidants. Ngolwazi oluthile lokhuseleko, bhekisa kwiPhepha leDatha loKhuseleko lweMichiza (MSDS) okanye ulwazi olufanelekileyo olunikwe ngumthengisi.
