I-Tetrahydropapaverine hydrochloride(CAS#6429-04-5)

I-Tetrahydropapaverine hydrochloride (i-CAS # 6429-04-5) i-compound ebambe ukubaluleka okubalulekileyo kwiinkalo ezifana neyeza.
Ngokubonakalayo, ihlala ibonakala njengomgubo omhlophe wekristale kunye nozinzo oluhle lwe-slid-state, okwenza kube lula ukuyigcina kunye nokuthutha. Ngokubhekiselele kwi-solubility, inomlinganiselo othile wokunyibilika emanzini, okuvumela ukuba uhlakazeke kangcono kwimidiya yamanzi xa usenza amalungiselelo ahambelanayo. Kwangaxeshanye, inokuphinda ibonise iimpawu ezithile zokunyibilika kwezinye izinyibilikisi eziphilayo, ezifana ne-methanol, i-ethanol kunye nezinye izinyibilikisi ze-alcohol organic.
Ukususela kumbono wesakhiwo sekhemikhali, isakhiwo sayo se-molecular sine-nitrogen-containing heterocyclic moiety ekhethekileyo, eyinika isiseko esikhethekileyo se-pharmacological ehlobene. Inokunxibelelana nezinye iithagethi zebhayoloji emzimbeni, njengezamkeli ezithile, ii-enzymes, njl. Ngaphezu koko, ubukho be-hydrochloric acid abunandisi nje kuphela ukunyibilika kwayo yonke i-compound emanzini, kodwa kuchaphazela ukuzinza kwayo kweekhemikhali kunye neempawu ezinxulumene nazo ezifana nemetabolism yeziyobisi ukuya kwinqanaba elithile.
Kwintsimi yesicelo, isetyenziswa kakhulu kwishishini lamachiza njengesithako esisebenzayo soxubo, ngokuqhelekileyo isetyenziselwa ukunciphisa izifo ezihambelanayo ezifana ne-vascular spasm. Ngokuphumla kwe-vascular smooth muscle kunye nokuphucula ukujikeleza kwegazi lendawo, kunefuthe elihle kunyango lwe-adjuvant yezinye izifo ze-cardiovascular and cerebrovascular, kwaye zinokunceda ukunciphisa iimpawu ezingathandekiyo ezibangelwa yi-vascular spasm kunye nokuphucula umgangatho wobomi bezigulane.
Ngexesha lokugcinwa kunye nokusetyenziswa, kubalulekile ukuyibeka kwindawo evaliweyo kunye neyomileyo ukuphepha umswakama, njengoko umswakama unokuchaphazela ukuzinza kwayo kweekhemikhali kunye ne-crystalline state. Ngelo xesha, kufuneka igcinwe phantsi kweemeko zokushisa ezimiselweyo, kude neendawo eziphezulu zokushisa, ukuthintela ukubola kunye ne-denaturation, kwaye ulandele ngokungqongqo imimiselo efanelekileyo yokugcinwa kweziyobisi kunye nokusetyenziswa ukuqinisekisa ukhuseleko kunye nokusebenza kakuhle kwamayeza.