Z-DL-ALA-OH(CAS# 4132-86-9)
| Inkcazelo yoKhuseleko | 24/25-Kuphephe ukudibana nolusu kunye namehlo. |
| WGK eJamani | 3 |
| Ikhowudi ye-HS | 29242990 |
Intshayelelo
I-N-Carbobenzyloxy-DL-alanine yi-organic compound, edla ngokufinyezwa njenge-Cbz-DL-Ala. Oku kulandelayo yinkcazo yobume bayo, ukusetyenziswa, ukuqulunqwa kunye nolwazi lokhuseleko:
Indalo:
I-N-Carbobenzyloxy-DL-alanine yikristale emhlophe eqinile kunye ne-molecular formula ye-C12H13NO4 kunye ne-molecular mass ye-235.24. Inamaziko amabini e-chiral kwaye ke ibonisa i-isomers yamehlo. Inokunyibilika kwii-solvents ezininzi zezinto eziphilayo, ezifana notywala kunye ne-dimethylformamide. Yinkomponi ezinzile kwaye kunzima ukubola.
Sebenzisa:
I-N-Carbobenzyloxy-DL-alanine yinto eqhelekileyo yokukhusela i-amino acid derivative. Ingasetyenziswa ekudityanisweni kweepeptides kunye neeproteni apho amaqela ayo e-carboxyl kunye ne-amine anokunxibelelana ngokusabela kwe-condensation phakathi kwe-amino acids ukwenza amatyathanga e-peptide. Iqela elikhuselayo le-N-benzyloxycarbonyl linokususwa ngeemeko ezifanelekileyo emva kokugqitywa kwempendulo yokubuyisela isakhiwo sokuqala se-amino acid.
Indlela yokulungiselela:
Ukulungiswa kwe-N-Carbobenzyloxy-DL-alanine ngokuqhelekileyo kuqhutywa kusetyenziswa i-N-benzyloxycarbonyl-alanine kunye nesixa esifanelekileyo se-DCC (diisopropylcarbamate) kwi-solvent efanelekileyo. I-reaction dehydrates ukwenza i-amide structure, ethi ke ihlanjululwe yi-crystallization ukunika imveliso efunekayo.
Ulwazi ngoKhuseleko:
I-N-Carbobenzyloxy-DL-alanine zikhuselekile xa zisetyenziswa phantsi kweemeko ezifanelekileyo zokusebenza. Nangona kunjalo, njengoko iyikhemikhali, izikhokelo zeendlela ezikhuselekileyo zaselabhoratri zisafuna ukulandelwa. Inokucaphukisa amehlo kunye nolusu, ke nxiba izixhobo ezifanelekileyo zokuzikhusela ezinje ngeeglavu kunye neeglavu ngexesha lokusebenza. Ukongezelela, kufuneka igcinwe kwindawo eyomileyo, enomoya, kude nomlilo kunye nezinto ezinokutsha. Ukufumana ulwazi oluthe vetshe malunga nokuphatha nokuphatha ngokukhuselekileyo, jonga kwiphepha leenkcukacha zokhuseleko ezifanelekileyo (SDS) zekhemikhali okanye udibane nochwepheshe.
