Z-PYR-OH(CAS# 32159-21-0)
| Iikhowudi zoMngcipheko | R22/22 - R36/37/38 – Ukucaphuka kwamehlo, inkqubo yokuphefumla kunye nolusu. |
| Inkcazelo yoKhuseleko | S22 – Musa ukuphefumla uthuli. S24/25-Kuphephe ukudibana nolusu namehlo. S44 - S35 – Esi sixhobo kunye nesingxobo saso kufuneka silahlwe ngendlela ekhuselekileyo. S28 – Emva kokudibana nolusu, hlamba ngoko nangoko ngeesepha ezininzi. S7 – Gcina isikhongozeli sivalwe ngokuqinileyo. S4 - Gcina kude neendawo zokuhlala. |
| WGK eJamani | 3 |
| Ikhowudi ye-HS | 29337900 |
Intshayelelo
I-Cbz-pyroglutamic acid (carbobenzoxy-L-phenylalanine) i-organic compound esetyenziswa ngokuqhelekileyo njengeqela elikhuselayo le-amino acid kwi-chemistry. Iimpawu zayo zeekhemikhali zimhlophe ngekristale eqinileyo, i-soluble kwi-solvents eziphilayo ezifana ne-ethanol kunye ne-chloroform, enganyibiliki emanzini.
Enye yezinto eziphambili zokusetyenziswa kwe-CBZ-pyroglutamic acid kukusebenza njengeqela elikhuselayo le-amino acids kwi-slide-phase synthesis. Inokwenza isakhiwo se-amide esizinzileyo ngokusabela kunye neqela le-α-amino le-amino acids ukukhusela ezinye iimpendulo ukuba zenzeke. Xa udibanisa i-peptides okanye iiprotheni, i-Cbz-pyroglutamic acid ingasetyenziselwa ukukhusela ngokukhethekileyo iintsalela ze-amino acid.
Indlela yokulungiselela i-Cbz-pyroglutamic acid idla ngokusabela kwi-pyroglutamic acid kunye ne dibenzoyl carbonate (elungiswe yi-reaction ye dibenzoyl chloride kunye ne-sodium carbonate) phantsi kweemeko zealkali. Inkqubo yokulungiselela kufuneka iphathwe ngononophelo ukuphepha ukuphendula kwecala okanye izinto eziyingozi.
Ulwazi lokhuseleko: I-Cbz-pyroglutamic acid yinto enokutsha, thintela ukudibana ngqo nemithombo yokutshisa. Izixhobo ezifanelekileyo zokukhusela, ezinjengeeglavu zaselabhoratri kunye neeglasi, kufuneka zinxitywe ngexesha lokuphatha. Kuphephe ukuphefumla uthuli lwayo okanye isisombululo njengoko kunokubangela ukucaphuka kwinkqubo yokuphefumla. Ngexesha lokugcinwa kunye nokuphatha, kufuneka kuthathelwe ingqalelo ukutywina isitya kwaye usigcine kude nemithombo yomlilo kunye nezinto ezinokutsha.
